High Seroprevalence of CMV Among Women of Childbearing Age Implicates High Burden of Congenital Cytomegalovirus Infection in Poland

Cytomegaloviruses are common worldwide, with variable frequency of infections. The infection in pregnancy may lead to pregnancy loss or serious sequelae for the child. To understand the risk posed by CMV in Poland we conducted cross-sectional study on women aged 15-49 basing on existing serum bank....

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Bibliographic Details
Published in:Polish journal of microbiology 2016-01, Vol.65 (4), p.425-432
Main Authors: Siennicka, Joanna, Dunal-Szcepaniak, Milena, Trzcińska, Agnieszka, Godzik, Paulina, Rosińska, Magdalena
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age
Analysis
Banks (Finance)
Births
CMV IgG prevalence
CMV in Poland
Complications
congenital CMV infection
congenital CMV sequelae
Congenital infection
Cytomegalovirus
Cytomegalovirus infections
Cytomegalovirus Infections - congenital
Cytomegalovirus Infections - epidemiology
Female
Health aspects
Humans
Immunoglobulin G
Infant, Newborn
Infection
Infectious Disease Transmission, Vertical
Middle Aged
Poland - epidemiology
Pregnancy
Secondary infection
Seroepidemiologic Studies
Serology
Socioeconomic factors
women of childbearing age
Womens health
Young Adult
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Summary:Cytomegaloviruses are common worldwide, with variable frequency of infections. The infection in pregnancy may lead to pregnancy loss or serious sequelae for the child. To understand the risk posed by CMV in Poland we conducted cross-sectional study on women aged 15-49 basing on existing serum bank. Age dependent incidence, the rates of congenital infection and sequelae were modelled from sero-prevalence, literature and demographic data. The overall anti-CMV IgG prevalence was 81.9% increasing from 74.3% in
ISSN:1733-1331
2544-4646
2544-4646
DOI:10.5604/17331331.1227668