Ligation of left gastric vein may cause delayed gastric emptying after pancreatoduodenectomy: a retrospective study

• Published in: BMC gastroenterology 2022-08, Vol.22 (1), p.1-398, Article 398
• Main Authors: Kimura, Koichi, Minagawa, Ryosuke, Izumi, Takuma, Otake, Akihiko, Aoyagi, Takehiko, Taniguchi, Daisuke, Yano, Hiroko, Kajiwara, Yuichiro, Minami, Kazuhito, Nishizaki, Takashi
• Format: Article
• Language: English
• Subjects: Abdomen; Bile ducts; Complications and side effects; Dissection; Fistula; Gastric emptying; Gastroenterology; Hepatic artery; Jaundice; Ligature (Surgery); Lymph nodes; Lymphatic system; Methods; Multivariate analysis; Obstructive jaundice; Pancreatic fistula; Pancreaticoduodenectomy; Patients; Physiological aspects; Portal vein; Risk factor; Risk factors; Running; Sepsis; Spleen; Splenic artery; Stomach; Surgery; Tomography; Tumors; Veins & arteries; Vena cava
• ISSN: 1471-230X; 1471-230X
• DOI: 10.1186/s12876-022-02478-5

Background This study aimed to determine which running pattern of the left gastric vein (LGV) is most frequently ligated in subtotal stomach-preserving pancreatoduodenectomy (SSPPD) and how LGV ligation affects delayed gastric emptying (DGE) after SSPPD. Methods We retrospectively analysed 105 patients who underwent SSPPD between January 2016 and September 2021. We classified the running pattern of LGV as follows: type 1 runs dorsal to the common hepatic artery (CHA) or splenic artery (SpA) to join the portal vein (PV), type 2 runs dorsal to the CHA or SpA and joins the splenic vein, type 3 runs ventral to the CHA or SpA and joins the PV, and type 4 runs ventral to the CHA or SpA and joins the SpV. Univariate and multivariate analyses were used to identify differences between patients with and without DGE after SSPPD. Results Type 1 LGV running pattern was observed in 47 cases (44.8%), type 2 in 23 (21.9%), type 3 in 12 (11.4%), and type 4 in 23 (21.9%). The ligation rate was significantly higher in type 3 (75.0%) LGVs (p < 0.0001). Preoperative obstructive jaundice (p = 0.0306), LGV ligation (p < 0.0001), grade B or C pancreatic fistula (p = 0.0116), and sepsis (p = 0.0123) were risk factors for DGE in the univariate analysis. Multivariate analysis showed that LGV ligation was an independent risk factor for DGE (odds ratio: 13.60, 95% confidence interval: 3.80-48.68, p < 0.0001). Conclusion Type 3 LGVs are often ligated because they impede lymph node dissection; however, LGV preservation may reduce the occurrence of DGE after SSPPD. Keywords: Obstructive jaundice, Pancreatic fistula, Risk factor, Sepsis, Stomach