Early rehabilitation program and weaning outcomes in critically ill chronic obstructed airway disease patients: a randomized trial

Background To compare the effectiveness of early rehabilitation program on mechanical ventilated COPD patient in RICU to those using current usual care regarding diaphragm function and weaning outcomes. Methods The study was a randomized controlled trial. It included 108 newly admitted COPD patients...

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Bibliographic Details
Published in:The Egyptian Journal of Bronchology 2022-12, Vol.16 (1), p.32-9, Article 32
Main Authors: Shaaban, Lamiaa, Abdeen, Ashraf, Saleh, Hend Mohamed, Mahran, Safaa A., Farghaly, Shereen
Format: Article
Language:English
Subjects:
Chronic obstructive pulmonary disease
Diabetes
Early rehabilitation program
Hospitals
Hypertension
Intensive care
Intensive care unit
Laboratories
Mechanical ventilation
Medicine
Medicine & Public Health
Mortality
Neuromuscular electrical stimulation
Patients
Rehabilitation
Ventilators
Weaning
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Summary:Background To compare the effectiveness of early rehabilitation program on mechanical ventilated COPD patient in RICU to those using current usual care regarding diaphragm function and weaning outcomes. Methods The study was a randomized controlled trial. It included 108 newly admitted COPD patients to RICU, Chest Department, Assiut University Hospital, Egypt, in the period from June 2018 to May 2020. They were divided into two groups: group Ι received the usual care plus pulmonary rehabilitation program, and group II received the usual care alone. The outcomes (MV duration, rates of successful weaning, diaphragm function, and lengths of hospital and ICU stay) were recorded and evaluated. The data was analyzed using Student t -test, Mann–Whitney U-test, Wilcoxon signed-rank test, chi-square ( χ 2 ) test or Fisher Exact test, receiver operating characteristics (ROC) curve, and logistic regression analysis. Results One-hundred and eight COPD patients were included. Early rehabilitation program for COPD patients in the ICU shortened the duration of their MV, increases the rates of successful weaning and decreases 30-day mortality, and shortened the duration of their ICU and hospital stays, as compared to COPD patients who received usual care. Conclusions Management of COPD patients with early rehabilitation program is associated with better outcome with improvement of the quality of life of COPD patients. Trial registration Clinical trial.gov : NCT03253380
ISSN:1687-8426
2314-8551
DOI:10.1186/s43168-022-00128-8