Coccidioidomycosis in Joint Replacement: A Review of the Literature With Case Presentations

Coccidioidomycosis is a fungal infection endemic to certain regions of the Americas. In some cases, the organism may infect the musculoskeletal system, resulting in a prosthetic joint infection (PJI). Due to its difficulty in diagnosis, treatment of coccidioidomycosis in PJI is often delayed. Furthe...

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Bibliographic Details
Published in:Arthroplasty today 2023-06, Vol.21, p.101123, Article 101123
Main Authors: Giordani, Francesca Anna, Kiernan, Brendan, Giordani, Mauro, Darrow, Morgan, Thorpe, Steven, Meehan, John P.
Format: Article
Language:English
Subjects:
Case Report
Coccidiomycosis
Fungal
Hip replacement
Knee replacement
Prosthetic joint infection
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Summary:Coccidioidomycosis is a fungal infection endemic to certain regions of the Americas. In some cases, the organism may infect the musculoskeletal system, resulting in a prosthetic joint infection (PJI). Due to its difficulty in diagnosis, treatment of coccidioidomycosis in PJI is often delayed. Furthermore, with limited number of case reports, a standard of care in treatment has yet to be established. We present 2 cases of coccidioidomycosis PJI, the extensive evaluation that led to the diagnosis, and the treatment provided. This report highlights the natural progression of coccidioidomycosis in a prosthetic joint, the diagnostic features including histology, advanced imaging, and final treatment administered.
ISSN:2352-3441
2352-3441
DOI:10.1016/j.artd.2023.101123