Is Panoramic Radiography Really a Key Examination before Chemo-Radiotherapy Treatment for Oropharyngeal Cancer?

• Published in: Applied sciences 2021-09, Vol.11 (17), p.7965
• Main Authors: Bosoni, Carlo, Pietragalla, Michele, Maraghelli, Davide, Rastrelli, Vieri, Locatello, Luca Giovanni, Desideri, Isacco, Giuntini, Veronica, Franchi, Lorenzo, Nardi, Cosimo
• Format: Article
• Language: English
• Subjects: Accuracy; apical periodontitis; Cancer; Chemotherapy; Computed tomography; Dental caries; Dental materials; diagnostic accuracy; Diagnostic systems; Disease; Evaluation; Health services; Human papillomavirus; Maxillofacial; Medical imaging; Medical prognosis; Oropharyngeal cancer; panoramic radiography; Patients; Periodontal disease; Periodontal diseases; Periodontitis; Radiation therapy; Radiography; radiotherapy; Sensitivity analysis; Statistical analysis; Teeth
• ISSN: 2076-3417; 2076-3417
• DOI: 10.3390/app11177965

Aim: To evaluate the diagnostic accuracy of panoramic radiography (PAN) for the identification of infectious foci of the tooth and periradicular bone before definitive chemo-radiotherapy treatment for oropharyngeal cancer, using multislice spiral computed tomography (MSCT) imaging as the reference standard. Materials and methods: 50 patients with oropharyngeal cancer who had performed both pre-treatment MSCT and PAN were retrospectively evaluated. Pre-radiotherapy MSCT showed 65 deep caries, 37 root remnants, 143 stage III periodontal diseases, and 77 apical periodontitis, for a total of 322 infectious foci. The same number of healthy teeth (control group) was selected via MSCT to be analysed by PAN. Sensitivity, specificity, positive and negative predictive values, and diagnostic accuracy for PAN images with respect to MSCT imaging were examined. Results: PAN showed sensitivity, negative predictive value, and diagnostic accuracy of 100% for deep caries, root remnants, and stage III periodontal disease, whereas there were 46.8%, 64.7%, and 72.1% apical periodontitis respectively. Conclusions: PAN did not show great diagnostic accuracy in the assessment of apical periodontitis, and therefore maxillofacial MSCT carried out before chemo-radiotherapy treatment should always be examined to identify dental and jaw diseases. Deep caries, root remnants, and stage III periodontal disease were perfectly detected on PAN.