One-pot synthesis of highly substituted dihydro-2-oxopyrols using nano-SnCl4/γ-Al2O3 as a mild solid lewis acid catalyst

[Display omitted] In this paper, highly substituted dihydro-2-oxopyrol derivatives were synthesized through a three component reaction of dialkylacetylenedicarboxylate, formaldehyde and aniline derivatives in the presence of nano-SnCl4/γ-Al2O3. The reaction was proceeded in ethanol as the solvent un...

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Bibliographic Details
Published in:Results in Chemistry 2024-08, Vol.10, p.101690, Article 101690
Main Authors: Yaghmaeiyan, Nahid, Mirzaei, Mahdi, Bamoniri, Abdolhamid, Delghavi Khalifelou, Reza
Format: Article
Language:English
Subjects:
Acid catalyst
Dihydro-2-oxopyrols
Heterogeneous
Highly substituted
Nano-SnCl4/γ-Al2O3
One pot synthesis
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Summary:[Display omitted] In this paper, highly substituted dihydro-2-oxopyrol derivatives were synthesized through a three component reaction of dialkylacetylenedicarboxylate, formaldehyde and aniline derivatives in the presence of nano-SnCl4/γ-Al2O3. The reaction was proceeded in ethanol as the solvent under reflux conditions. Nano-SnCl4/γ-Al2O3 was prepared via the reaction of SnCl4 with nano-γ-Al2O3 and characterized by FT-IR, XRD, FE-SEM, TEM, EDS,EDS-mapping, BET and TGA. Reusability of nano-SnCl4/γ-Al2O3 was examined in five runs, successfully. Short time of the reactions, good to excellent yield of products, heterogeneous conditions and reusability of the nano-catalyst are some of advantages of this green and environmental methodology.
ISSN:2211-7156
2211-7156
DOI:10.1016/j.rechem.2024.101690