Effects of donors’ and recipients’ preoperative serum sodium on the prognosis of liver transplantation

Dysnatremia is common in donors and recipients of liver transplantation (LT). However, the influence of dysnatremia on LT prognosis remains controversial. This study aimed to investigate effects of donors’ and recipients’ serum sodium on LT prognosis. We retrospectively reviewed 248 recipients who u...

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Bibliographic Details
Published in:Scientific reports 2024-09, Vol.14 (1), p.20304-8, Article 20304
Main Authors: Chen, Yabin, Li, Hao, Zhang, Menggang, Wu, Zeyu, Fang, Haoran, Wen, Peihao, Zhang, Jiakai, Guo, Wenzhi
Format: Article
Language:English
Subjects:
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Adult
Aged
Bilirubin
Bilirubin - blood
Blood Urea Nitrogen
Creatinine
Creatinine - blood
Donors
Dysnatremia
Female
Humanities and Social Sciences
Humans
Hypernatremia
Hyponatremia
Hyponatremia - blood
Liver transplantation
Liver Transplantation - adverse effects
Liver transplants
Male
Medical prognosis
Middle Aged
multidisciplinary
Preoperative Period
Prognosis
Renal function
Retrospective Studies
Science
Science (multidisciplinary)
Sodium
Sodium - blood
Survival
Tissue Donors
Transplant Recipients
Urea
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Summary:Dysnatremia is common in donors and recipients of liver transplantation (LT). However, the influence of dysnatremia on LT prognosis remains controversial. This study aimed to investigate effects of donors’ and recipients’ serum sodium on LT prognosis. We retrospectively reviewed 248 recipients who underwent orthotopic LT at our center between January 2016 and December 2018. Donors and recipients perioperative and 3-year postoperative clinical data were included. Delta serum sodium was defined as the donors’ serum sodium minus the paired recipients’ serum sodium. Donors with serum sodium > 145 mmol/L had significantly higher preoperative blood urea nitrogen (BUN) ( P  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-71218-4