Uptake of intermittent preventive treatment and pregnancy outcomes: health facilities and community surveys in Chókwè district, southern Mozambique

Malaria in pregnancy leads to serious adverse effects on the mother and the child and accounts for 75,000-200,000 infant deaths every year. Currently, the World Health Organization recommends intermittent preventive treatment of malaria in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) at each...

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Bibliographic Details
Published in:Malaria journal 2018-03, Vol.17 (1), p.109-109, Article 109
Main Authors: Arnaldo, Paulo, Rovira-Vallbona, Eduard, Langa, Jerónimo S, Salvador, Crizolgo, Guetens, Pieter, Chiheb, Driss, Xavier, Bernardete, Kestens, Luc, Enosse, Sónia M, Rosanas-Urgell, Anna
Format: Article
Language:English
Subjects:
Antimalarials - administration & dosage
Antimalarials - therapeutic use
Coverage
Drug Combinations
Female
Health Facilities
Humans
Insecticide-Treated Bednets
IPTp-SP
Labor, Obstetric
Malaria
Mozambique
Pregnancy
Pregnancy Complications, Parasitic - prevention & control
Pyrimethamine - administration & dosage
Pyrimethamine - therapeutic use
Risk Factors
Sulfadoxine - administration & dosage
Sulfadoxine - therapeutic use
Young Adult
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Summary:Malaria in pregnancy leads to serious adverse effects on the mother and the child and accounts for 75,000-200,000 infant deaths every year. Currently, the World Health Organization recommends intermittent preventive treatment of malaria in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) at each scheduled antenatal care (ANC) visit. This study aimed to assess IPTp-SP coverage in mothers delivering in health facilities and at the community. In addition, factors associated with low IPTp-SP uptake and malaria adverse outcomes in pregnancy were investigated. A community and a health facility-based surveys were conducted in mothers delivering in Chókwè district, southern Mozambique. Social-demographic data, malaria prevention practices and obstetric history were recorded through self-report and antenatal records. For women delivering at health facilities, a clinical examination of mother and child was performed, and malaria infection at delivery was determined by rapid diagnostic test, microscopy, quantitative PCR and placental histology. Of 1141 participants, 46.6, 30.2, 13.5 and 9.6% reported taking ≥ 3, two, one and none SP doses, respectively. Low IPTp uptake (
ISSN:1475-2875
1475-2875
DOI:10.1186/s12936-018-2255-z