Isothermal calorimetry calscreener in the metabolism gauge of human malignant neoplastic cells: a burgeoning nexus in cancer biochemical metrology and diagnostics

Background At present, the function of isothermal microcalorimetry (IMC) calscreener in detecting alterations in the metabolic pathways of cancer cells remains unexplored. We disclosed the shortcomings of current screening methods and the need for precise and dependable instruments in the detection...

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Published in:Bulletin of the National Research Centre 2023-12, Vol.47 (1), p.120-11, Article 120
Main Authors: Bayode, Michael Tosin, Alabi, Mercy Adewumi, Ibisanmi, Temitope Abraham, Okiti, Ayomide Faith, Adebisi, Olabisi Omowumi, Aro, Philemon Olayemi, Awode, Ayoola Emmanuel, Lawal, Oyindamola Sukurat, Babatunde, Olamide Joshua, Adenikinju, Gladys Oluwafisayo
Format: Article
Language:English
Subjects:
Agriculture
Calorimetry
Cancer
Cancer cells
Cancer diagnosis
Cancer metabolism
Cancer research
Cancer therapies
Cancer treatment
Effectiveness
Engineering
Heat measurement
Humanities and Social Sciences
IMC calscreener
Medical research
Medicine and Human Genetics
Metabolic pathways
Metabolic rate
Metabolism
multidisciplinary
Review
Science
Science (multidisciplinary)
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Summary:Background At present, the function of isothermal microcalorimetry (IMC) calscreener in detecting alterations in the metabolic pathways of cancer cells remains unexplored. We disclosed the shortcomings of current screening methods and the need for precise and dependable instruments in the detection and informed treatment of cancer via the IMC in relation to the experimental procedures required to obtain accurate results. Main body of abstract We examined the intricate technical aspects of isothermal calorimetry. The application of the IMC calscreener in cancer research is then discussed in depth, including how it can be used to evaluate the efficacy of treatments, identify metabolic inhibitors, and assess metabolic rates. We also investigated the diagnostic potential of isothermal calorimetry, particularly for early cancer detection and tracing therapy efficacy. Conclusions General findings shed light on the present issues and potential approaches for isothermal calorimetry application in cancer research and diagnosis. We underline the potential for isothermal calorimetry to fundamentally alter how to understand and treat cancer, as well as the need for additional studies to maximize its application in clinical settings. This in turn offers a thorough and fascinating account of the emerging relationship between isothermal calorimetry and cancer biochemistry, as well as its potential to revolutionize cancer detection and therapy.
ISSN:2522-8307
2522-8307
DOI:10.1186/s42269-023-01097-8