Association between serum vitamin D status and uterine leiomyomas: a case-control study

Uterine leiomyoma is a common gynecological condition that negatively affects women's quality of life. Vitamin D plays an important role in tumor development and progression. However, clinical studies comparing serum vitamin D levels between women with and without uterine leiomyomas are limited...

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Published in:Obstetrics & gynecology science 2024-01, Vol.67 (1), p.101-111
Main Authors: Okoro, Chukwuemeka Chukwubuikem, Ikpeze, Okechukwu Christian, Eleje, George Uchenna, Udigwe, Gerald Okanandu, Ezeama, Chukwuemeka Okwudili, Ugboaja, Joseph Odirichukwu, Enechukwu, Chukwunonso Isaiah, Umeononihu, Osita Samuel, Ogabido, Chukwudi Anthony, Oguejiofor, Charlotte Blanche, Njoku, Tobechi Kingsley, Egeonu, Richard Obinwanne, Okafor, Chigozie Geoffrey, Obiagwu, Hillary Ikechukwu, Onyejiaka, Chukwudubem Chinagorom, Obidike, Afam Ben, Onah, Christian Ejike, Uzukwu, Ifeanyi, Okoro, Amarachukwu Doris, Ezema, Evaristus Chino, Ibekwe, Adaobi Maryann, Ikechebelu, Joseph Ifeanyichukwu
Format: Article
Language:English
Subjects:
fibroid
hypovitaminosis d
leiomyoma
Original
vitamin d
vitamin d deficiency
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Summary:Uterine leiomyoma is a common gynecological condition that negatively affects women's quality of life. Vitamin D plays an important role in tumor development and progression. However, clinical studies comparing serum vitamin D levels between women with and without uterine leiomyomas are limited and inconclusive. This study aimed to compare serum vitamin D levels in women with and without uterine leiomyomas. This hospital-based case-control study included 150 women who visited a gynecological clinic. The cases included 75 women with uterine leiomyoma, whereas the controls included 75 age-and parity-matched participants without uterine leiomyoma. Serum vitamin D levels were measured in each participant and volumes of the uterine leiomyomas were determined using the water displacement method following myomectomy. The statistical significance was inferred at P
ISSN:2287-8572
2287-8580
DOI:10.5468/ogs.23143