Conjoint analysis of clinical, imaging, and pathological features of schistosomiasis and colorectal cancer

• Published in: Pathology oncology research 2023-11, Vol.29, p.1611396-1611396
• Main Authors: Zhang, Fang, Wang, XiaoShuang, Zhu, YuanTing, Xia, Peng
• Format: Article
• Language: English
• Subjects: colorectal cancer; imaging; pathology; Pathology and Oncology Archive; schistosomiasis; t stage
• ISSN: 1532-2807; 1219-4956; 1532-2807
• DOI: 10.3389/pore.2023.1611396

This study aims to examine and compare clinical, radiological, and pathological data between colorectal cancer (CRC) patients with and without schistosomiasis and uncover distinctive CRC characteristics when accompanied by schistosomiasis. This retrospective study is based on data collected from 341 patients diagnosed with CRC post-surgery and pathology. Of these patients, 101 (Group A) were diagnosed with colorectal cancer co-occurring with schistosomiasis (CRC-S), while 240 patients (Group B) were diagnosed with colorectal cancer without concurrent schistosomiasis (CRC-NS). Both groups were compared and analyzed based on their clinical data, imaging-based TNM staging, lymph node metastasis, nerve invasion, vascular cancer thrombus, and histopathological differentiation. A Chi-squared test revealed a significant difference in gender distribution between the patients with CRC-S (Group A) and CRC-NS (Group B), with a -value of 0.043 and χ = 4.115. Specifically, a higher incidence rate was observed among males in Group A. There was a difference in the overall distribution of TNM staging between the two groups ( = 0.034, χ = 6.764). After pairwise comparison, a statistically significant difference was observed in the T3 stage (