Too Much of a Good Thing: Rethinking Feed Formulation and Feeding Practices for Zinc in Swine Diets to Achieve One Health and Environmental Sustainability

• Published in: Animals (Basel) 2022-11, Vol.12 (23), p.3374
• Main Authors: Shurson, Gerald C, Urriola, Pedro E, Hung, Yuan-Tai
• Format: Article
• Language: English
• Subjects: Agricultural land; Animal nutrition; Antimicrobial agents; Antimicrobial resistance; Antioxidants; Bioavailability; biomarkers; Diarrhea; Dietary minerals; Drug resistance; environmental impacts; Enzymes; Excretion; Feed formulation; Feeding; feeding practices; Feeds; Free radicals; Gene expression; Gestation; growth promotion; Hogs; Homeostasis; Inflammation; Low birth weight; Manures; Metabolism; Mortality; Nutrient concentrations; Nutrition; Oxidative stress; Pharmacology; Pig manure; Pollution; Pollution control; Pork; Productivity; Proteins; Regulations; Retention; Review; Small intestine; Sustainability; Sustainable development; Swine; Weaning; Zinc; Zinc oxide; Zinc oxides
• ISSN: 2076-2615; 2076-2615
• DOI: 10.3390/ani12233374

The objectives of this review were to summarize current knowledge of Zn in swine nutrition, environmental concerns, potential contribution to antimicrobial resistance, and explore the use of alternative feeding strategies to reduce Zn excretion in manure while capturing improvements in productivity. Zinc is a required nutrient for pigs but is commonly supplemented at concentrations that greatly exceed estimated requirements. Feeding pharmacological concentrations of Zn from ZnO to pigs for 1 to 2 weeks post-weaning reduces post-weaning diarrhea and improves growth performance. Feeding elevated dietary levels of Zn to sows during the last 30 days of gestation can reduce the incidence of low-birth-weight pigs and pre-weaning mortality. Most of the dietary Zn consumed by pigs is not retained in the body and is subsequently excreted in manure, which led several countries to impose regulations restricting dietary Zn concentrations to reduce environmental impacts. Although restricting Zn supplementation in swine diets is a reasonable approach for reducing environmental pollution, it does not allow capturing health and productivity benefits from strategic use of elevated dietary Zn concentrations. Therefore, we propose feeding strategies that allow strategic use of high dietary concentrations of Zn while also reducing Zn excretion in manure compared with current feeding practices.