Biomarkers and Human Biomonitoring in Occupational Medicine

Over the last years, biomarkers have increasingly expanded and become early and specific end points for monitoring cellular responses to various disease states and exposures to drugs and chemical agents. They have enjoyed some success as predictors of health outcomes for a number of clinical disease...

Full description

Saved in:
Bibliographic Details
Published in:Applied sciences 2020-09, Vol.10 (18), p.6181
Main Authors: Ledda, Caterina, Rapisarda, Venerando
Format: Article
Language:English
Subjects:
Aging
Biomarkers
Biomonitoring
Body mass index
Chemical agents
Chromosomes
Deoxyribonucleic acid
DNA
DNA methylation
DNA repair
Drug dosages
effect
Enzymes
Epigenetics
Exposure
Investigations
Medicine
Metabolism
Metabolites
occupational medicine
Risk assessment
susceptibility
Systematic review
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Over the last years, biomarkers have increasingly expanded and become early and specific end points for monitoring cellular responses to various disease states and exposures to drugs and chemical agents. They have enjoyed some success as predictors of health outcomes for a number of clinical diseases, but their application for chemical exposure risk assessments has been more limited. Biomarkers may be classified into markers of exposure, effect, and susceptibility. To be useful in providing linkage to human exposure, biomarkers should be as specific as possible to the exposure agents and highly sensitive, so to detect even low levels of exposure.
ISSN:2076-3417
2076-3417
DOI:10.3390/app10186181