Pregnancy Followed by Delivery May Affect Circulating Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels in Women of Reproductive Age

It is known that menopause or lack of endogenous estrogen is a risk factor for endothelial dysfunction and CAD. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is involved inmultiple phases of vascular dysfunction.The purpose of the current study was to determine the association betw...

Full description

Saved in:
Bibliographic Details
Published in:Mediators of Inflammation 2012-01, Vol.2012 (2012), p.723-729-180
Main Authors: Baydas, Adil, Kobat, M. Ali, Çelik, Ahmet, Balin, Mehmet
Format: Article
Language:English
Subjects:
Adult
Arteriosclerosis - blood
Arteriosclerosis - prevention & control
Endothelium, Vascular - metabolism
Endothelium, Vascular - pathology
Enzyme-Linked Immunosorbent Assay - methods
Female
Gene Expression Regulation
Humans
Pregnancy
Scavenger Receptors, Class E - blood
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:It is known that menopause or lack of endogenous estrogen is a risk factor for endothelial dysfunction and CAD. Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is involved inmultiple phases of vascular dysfunction.The purpose of the current study was to determine the association between soluble LOX-1 (sLOX-1) and pregnancy followed by delivery in women of reproductive age. Materials/Methods. Sixty-eight subjects with pregnancy followed by delivery (group 1) and 57 subjects with nongravidity (group 2) were included in this study. Levels of sLOX-1 were measured in serum by EL SA. Results. Plasma levels of sLOX-1 were significantly lower in Group 1 than Group 2 in women of reproductive age (0.52±0.18 ng/mL and 0.78±0.13, resp., P
ISSN:0962-9351
1466-1861
DOI:10.1155/2012/837375