Metastatic primary neuroendocrine carcinoma of the breast (NECB)

Abstract Neuroendocrine carcinoma of the breast (NECB) is a subtype of breast cancer. The diagnostic criteria of primary NECB were established in 2003 and updated in 2012. It is a rare entity, and few studies have reported the histogenesis, immunohistochemistry for a pathological diagnosis, clinical...

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Bibliographic Details
Published in:Journal of cancer research and practice 2018-03, Vol.5 (1), p.38-42
Main Authors: Tsai, Tsung-Hsien, Hsieh, Pin-Pen, Hong, Ying-Chung, Yeh, Chang-Hong, Yu, Lennex Hsueh-Lin, Yu, Ming-Sun
Format: Article
Language:English
Subjects:
Diagnosis
Hematology, Oncology, and Palliative Medicine
Neuroendocrine breast carcinoma
Neuroendocrine differentiation
Neuroendocrine markers
Treatment
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Summary:Abstract Neuroendocrine carcinoma of the breast (NECB) is a subtype of breast cancer. The diagnostic criteria of primary NECB were established in 2003 and updated in 2012. It is a rare entity, and few studies have reported the histogenesis, immunohistochemistry for a pathological diagnosis, clinical behavior, therapeutic strategies, and the prognostic factors. Because of the rarity of this disease, consistent diagnostic criteria will remind physicians of this disease when making a differential diagnosis to enable a timely diagnosis and prompt treatment. Herein, we report a case of primary NECB who presented with a history of right hip pain arising from an osteolytic lesion in the right acetabulum and ischium. The course of investigation started with metastasis in the right hip and concluded with a diagnosis of NECB. In addition to the case report, we also conducted a literature review.
ISSN:2311-3006
2311-3006
DOI:10.1016/j.jcrpr.2017.10.003