Comparative evaluation of two chelating agents in collagen fiber network modification over dentinal tubules: An in vitro analysis

To compare effectiveness of ethylenediaminetetraacetic acid (EDTA) and citric acid in removing collagen fiber network covering dentinal tubules of human teeth. Eighteen dentin discs were divided in three groups; Gp 1: discs received no treatment (control), Gp 2: discs etched with 17% EDTA (pH = 7.1)...

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Bibliographic Details
Published in:Saudi pharmaceutical journal 2020-06, Vol.28 (6), p.657-661
Main Authors: Khan, Abdul Samad, Farooq, Imran, Ali, Saqib, Khan, Soban Qadir, Hakeem, Abbas Saeed
Format: Article
Language:English
Subjects:
Citric acid
Dentin
Dentinal tubules
Ethylenediaminetetraacetic acid (EDTA)
SEM
XRD
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Summary:To compare effectiveness of ethylenediaminetetraacetic acid (EDTA) and citric acid in removing collagen fiber network covering dentinal tubules of human teeth. Eighteen dentin discs were divided in three groups; Gp 1: discs received no treatment (control), Gp 2: discs etched with 17% EDTA (pH = 7.1), and Gp 3: discs etched with 6 wt% citric acid (pH = 4.0). Scanning electron microscopy (SEM) was performed to assess collagen fiber removal and X-ray diffraction (XRD) was implemented to analyse crystal peaks of discs. The SEM analysis demonstrated more collagen removal with EDTA treatment compared to citric acid treated specimens. Grade 6 (81% to 100% fiber removal) was mostly achieved for Gp 2 samples whereas grade 2 (1% to 20% fiber removal) was mostly achieved for Gp 3 samples and inter-group comparisons between these groups were statistically significant (p 
ISSN:1319-0164
2213-7475
DOI:10.1016/j.jsps.2020.04.005