Comparative Analysis of the Measles Antibody Levels in Healthy Medical Personnel of Maternity Ward and Women in Labor

It has been proven that post-vaccination immunity to measles virus after two doses of vaccine is not able to persistently protect against infection throughout life. The goal of this research was to determine the immune layer to the measles virus among women in labor and maternity ward personnel in t...

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Bibliographic Details
Published in:Frontiers in immunology 2021-07, Vol.12, p.680506-680506
Main Authors: Kostinov, Mikhail Petrovich, Zhuravlev, Pavel Ivanovich, Gladkova, Lylia Solomonovna, Mashilov, Kirill Vadimovich, Polishchuk, Valentina Borisovna, Shmitko, Anna Dmitrievna, Zorina, Veronika Nikolaevna, Blagovidov, Dmitriy Alexeyevich, Pahomov, Dmitriy Vladimirovich, Vlasenko, Anna Egorovna, Ryzhov, Alexey Anatolevich, Khromova, Ekaterina Alexandrovna
Format: Article
Language:English
Subjects:
Immunology
maternity ward
measles IgG antibodies
measles prevention
seropositivity
women in labor
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Summary:It has been proven that post-vaccination immunity to measles virus after two doses of vaccine is not able to persistently protect against infection throughout life. The goal of this research was to determine the immune layer to the measles virus among women in labor and maternity ward personnel in the same medical institution. The levels of IgG antibodies to measles virus in the umbilical cord blood of 594 women in labor and 88 workers of the maternity ward were studied by ELISA. It was revealed that 22.7% of umbilical cord blood serum samples from parturient women and 21.4% of blood serum samples from maternity ward personnel were seronegative (
ISSN:1664-3224
1664-3224
DOI:10.3389/fimmu.2021.680506