Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019-2021)

Medicinal and aromatic plants are mainly characterized by the presence of different bioactive compounds which exhibit various therapeutic activities. In order to investigate the different pharmacological properties of different extracts, a multitude of research articles published in the period betwe...

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Bibliographic Details
Published in:Biomolecules (Basel, Switzerland) Switzerland), 2021-12, Vol.12 (1), p.20
Main Authors: Dalli, Mohammed, Bekkouch, Oussama, Azizi, Salah-Eddine, Azghar, Ali, Gseyra, Nadia, Kim, Bonglee
Format: Article
Language:English
Subjects:
Animals
Antioxidants
Bioactive compounds
Cancer
Cell growth
Fatty acids
Flavonoids
Humans
Inflammation
Medicinal plants
Molecular modelling
Nigella sativa
Nigella sativa - chemistry
oil
Oils & fats
organic extracts
Oxidative stress
pharmacological properties
Pharmacology
Phytochemicals - chemistry
Phytochemicals - therapeutic use
Phytotherapy
Review
Seeds
Steroids
thymoquinone
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Summary:Medicinal and aromatic plants are mainly characterized by the presence of different bioactive compounds which exhibit various therapeutic activities. In order to investigate the different pharmacological properties of different extracts, a multitude of research articles published in the period between 2019 and 2021 were obtained from different databases (Scopus, Science Direct, PubMed, and Web of Science), and then explored and analyzed. The analysis of the collected articles allows us to classify the phytochemicals and the pharmacological activities through their underlying molecular mechanisms, as well as to explore the pharmacological activities exhibited by several identified compounds in which allow a better understanding, and better elucidation, of the bioactive compounds responsible for the pharmacological effects. Also shown are the existence of other bioactive compounds that are still unexplored and could be of great interest. This review could be taken as a guide for future studies in the field.
ISSN:2218-273X
2218-273X
DOI:10.3390/biom12010020