Efficient Synthesis of Pyrazinoic Acid Hybrid Conjugates

Abstract Benzotriazole-activated pyrazinoic acid was utilized as a versatile building block for the efficient and convenient synthesis of novel hybrid conjugates of pyrazinoic acid with secondary amines via amino acid linkers in high yields.

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Bibliographic Details
Published in:SynOpen (2017) 2017-03, Vol.1 (1), p.0050-0058
Main Authors: Panda, Siva S., Asiri, Abdullah M., Elagawany, Mohamed, Buchanan, Devan D., Torkian, Behrad, Bathala, Keerthana, Thomas, Sean J., Capito, Jason E., Arshad, Muhammad N., Al-Romaizan, Abeer N.
Format: Article
Language:English
Subjects:
amino acids
antituberculosis
benzotriazole methodology
pyrazinamide
pyrazinoic acid
secondary amines
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Description
Summary:Abstract Benzotriazole-activated pyrazinoic acid was utilized as a versatile building block for the efficient and convenient synthesis of novel hybrid conjugates of pyrazinoic acid with secondary amines via amino acid linkers in high yields.
ISSN:2509-9396
2509-9396
DOI:10.1055/s-0036-1590800