Development and characterization of chitosan-collagen films loaded with honey

Abstract Biomaterials developed with biopolymers contribute to the healing process of healthy or diabetic patients. The objective of the present study was to evaluate the effect of honey incorporation (0.3, 0.6, and 1.2 g/100 mL) in chitosan/collagen/glycerol composite films. The Ch/Coll/1.2H films...

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Published in:Polímeros, ciência e tecnologia ciência e tecnologia, 2023-01, Vol.33 (3)
Main Authors: Mora-López, David Servín de la, Madera-Santana, Tomás Jesús, López-Cervantes, Jaime, Sánchez-Machado, Dalia Isabel, Ayala-Zavala, Jesús Fernando, Soto-Valdez, Herlinda
Format: Article
Language:English
Subjects:
antibacterial films
Apis mellifera
bioactive films
chitosan
collagen
POLYMER SCIENCE
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Summary:Abstract Biomaterials developed with biopolymers contribute to the healing process of healthy or diabetic patients. The objective of the present study was to evaluate the effect of honey incorporation (0.3, 0.6, and 1.2 g/100 mL) in chitosan/collagen/glycerol composite films. The Ch/Coll/1.2H films revealed the greatest percentage of elongation (27.10%) and Young´s modulus (65.58 MPa). The barrier properties (WVTR and WVP) exhibited a significant increase when the honey was incorporated into the films. The absorption capacity, solubility, and enzymatic biodegradability were lower in films containing honey. The chemical interactions between the functional groups of the films were verified by FTIR. The morphology studied by SEM confirmed the mixture’s homogeneity. Finally, all formulations exhibited antibacterial properties against Staphylococcus aureus, Pseudomonas aeruginosa, Listeria monocytogenes, and Salmonella Typhimurium. The aforementioned properties of formulated dressings are suitable for their potential application in chronic wounds.
ISSN:0104-1428
1678-5169
1678-5169
DOI:10.1590/0104-1428.20230031