Research Progress of the Antiviral Bioactivities of Natural Flavonoids

Flavonoids are now considered as an indispensable component in a variety of nutraceutical and pharmaceutical applications. Most recent researches have focused on the health aspects of flavonoids for humans. Especially, different flavonoids have been investigated for their potential antiviral activit...

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Bibliographic Details
Published in:Natural products and bioprospecting 2020-10, Vol.10 (5), p.271-283
Main Authors: Wang, Lin, Song, Junke, Liu, Ailin, Xiao, Bin, Li, Sha, Wen, Zhang, Lu, Yang, Du, Guanhua
Format: Article
Language:English
Subjects:
Antiviral bioactivities
Biomedical and Life Sciences
Bioorganic Chemistry
Cellular and molecular mechanisms
Food Science
Life Sciences
Medicinal Chemistry
Natural flavonoids
Pharmacology/Toxicology
Plant Biochemistry
Plant Sciences
Review
Therapeutic applications
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Summary:Flavonoids are now considered as an indispensable component in a variety of nutraceutical and pharmaceutical applications. Most recent researches have focused on the health aspects of flavonoids for humans. Especially, different flavonoids have been investigated for their potential antiviral activities, and several natural flavonoids exhibited significant antiviral properties both in vitro and in vivo. This review provides a survey of the literature regarding the evidence for antiviral bioactivities of natural flavonoids, highlights the cellular and molecular mechanisms of natural flavonoids on viruses, and presents the details of most reported flavonoids. Meanwhile, future perspectives on therapeutic applications of flavonoids against viral infections were discussed.
ISSN:2192-2195
2192-2209
DOI:10.1007/s13659-020-00257-x