Does microperimetry have a role in monitoring visual function in patients with Behçet uveitis?

To evaluate the change in time in visual acuity, central macular thickness (CMT), and microperimetry (MP) findings in Behçet uveitis (BU) patients who were in remission with maintenance therapy. This single center, retrospective, observational cohort study included twenty-five eyes of 25 patients wi...

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Bibliographic Details
Published in:BMC ophthalmology 2024-12, Vol.24 (1), p.540-5, Article 540
Main Authors: Değirmenci, Mehmet Fatih Kağan, Yalçındağ, F Nilüfer
Format: Article
Language:English
Subjects:
Acuity
Adolescent
Adult
Analysis
Atrophy
Average threshold
Behcet Syndrome - complications
Behcet Syndrome - physiopathology
Behçet uveitis
Care and treatment
Diabetes
Disease
Edema
Female
Humans
Inflammation
Macula Lutea - pathology
Macula Lutea - physiopathology
Male
Microperimetry
Middle Aged
Optical coherence tomography
Patient monitoring equipment
Patients
Political aspects
Remission
Remission (Medicine)
Retrospective Studies
Statistical analysis
Tomography
Tomography, Optical Coherence - methods
Uveitis
Uveitis - diagnosis
Uveitis - physiopathology
Visual acuity
Visual Acuity - physiology
Visual Field Tests - methods
Visual Fields - physiology
Visual function
Visual impairment
Visual perception
Visual thresholds
Young Adult
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Summary:To evaluate the change in time in visual acuity, central macular thickness (CMT), and microperimetry (MP) findings in Behçet uveitis (BU) patients who were in remission with maintenance therapy. This single center, retrospective, observational cohort study included twenty-five eyes of 25 patients with BU who were in remission during maintenance therapy. Best corrected visual acuity (BCVA), CMT, macular integrity index, average threshold, and fixation stabilities (P1 and P2) evaluated at six-month intervals were recorded. The changes in time were statistically analyzed. Paired samples t-test was used for normally distributed data and Wilcoxon rank test was performed for non-normally distributed data. The mean BCVA and CMT showed no significant changes after six months. Although the mean macular integrity index decreased and the mean fixation stabilities increased after six months, these findings were not statistically significant. The mean average threshold was 16.8 dB at baseline and it increased significantly to 19.3 dB in the sixth month (p 
ISSN:1471-2415
1471-2415
DOI:10.1186/s12886-024-03805-y