Phytochemical investigation and antimicrobial activity of Derris scandens

Different fractions of root and stem of Derris scandens demonstrated good antibacterial (Escherichia coli, and Bacillus megaterium), antialgal (Chlorella fusca), and antifungal (Microbotryum violaceum) activities. Phytochemical investigation resulted in isolation of scandenin, scandenin A, betulinic...

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Bibliographic Details
Published in:Journal of King Saud University. Science 2015-10, Vol.27 (4), p.375-378
Main Authors: Hussain, Hidayat, Al-Harrasi, Ahmed, Krohn, Karsten, Kouam, Simeon F., Abbas, Ghulam, Shah, Afzal, Raees, Muhammad Adil, Ullah, Riaz, Aziz, Shahid, Schulz, Barbara
Format: Article
Language:English
Subjects:
Antialgal
Antimicrobial
Coumarin
Derris scandens
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Summary:Different fractions of root and stem of Derris scandens demonstrated good antibacterial (Escherichia coli, and Bacillus megaterium), antialgal (Chlorella fusca), and antifungal (Microbotryum violaceum) activities. Phytochemical investigation resulted in isolation of scandenin, scandenin A, betulinic acid, lupeol, β-amyran-3-one, β-amyrin, β-sitosterol and ß-sitosterol glucopyranoside. Study showed that scandenin has strong antibacterial activity against B. megaterium and good antifungal and antialgal properties. Scandenin A showed good antibacterial, antifungal and antialgal properties.
ISSN:1018-3647
DOI:10.1016/j.jksus.2015.01.001