Monocyte to high-density lipoprotein cholesterol ratio and serum uric acid in Chinese adults: a cross-sectional study

Previous studies have shown that the monocyte to high-density lipoprotein cholesterol (HDL-C) ratio (MHR) is a predictor of various diseases such as coronary heart disease, diabetic microangiopathy, and metabolic syndrome. However, there are few scientific reports on the correlation between MHR and...

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Bibliographic Details
Published in:BMC endocrine disorders 2022-02, Vol.22 (1), p.48-48, Article 48
Main Authors: Li, Yuexi, Liu, Xiaoqin, Luo, Yuhan
Format: Article
Language:English
Subjects:
Adult
Adults
Analysis
Aspartate
Blood
Blood pressure
China
Cholesterol
Coronary heart disease
Cross-Sectional Studies
Dextrose
Female
Glucose
High-density lipoprotein cholesterol
Humans
Leukocyte Count
Lipoproteins, HDL - blood
Low density lipoproteins
Male
Measurement
Medical examination
Medical screening
Middle Aged
Monocyte to high-density lipoprotein cholesterol ratio
Monocytes
Serum uric acid
Uric acid
Uric Acid - blood
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Summary:Previous studies have shown that the monocyte to high-density lipoprotein cholesterol (HDL-C) ratio (MHR) is a predictor of various diseases such as coronary heart disease, diabetic microangiopathy, and metabolic syndrome. However, there are few scientific reports on the correlation between MHR and serum uric acid. The objective of this report is to explore the relationship between MHR and serum uric acid in Chinese adults. This cross-sectional study included 646 participants from southwest China who underwent a health examination at the Health Management Center of Deyang People's Hospital. The examination included blood pressure readings, routine blood tests (lipid, fasting glucose, serum transaminase, and serum uric acid levels), and various standardized questionnaires. We employed a generalized additive model and smoothed curve fitting to explore the relationship between MHR and serum uric acid levels. We then performed subgroup analyses to investigate the robustness of this relationship. After adjusting for confounders (age, sex, body mass index, systolic blood pressure, diastolic blood pressure, aspartate transaminase, alanine aminotransferase, fasting glucose, total cholesterol, low-density lipoprotein, smoking, drinking, and exercise status), MHR was found to be positively correlated with serum uric acid levels (P 
ISSN:1472-6823
1472-6823
DOI:10.1186/s12902-022-00966-z