lupus nephritis in a patient with retroviral infection

• Published in: Saudi journal of kidney diseases and transplantation 2019-03, Vol.30 (2), p.520-525
• Main Authors: Valavan, K. Thirumal, Hema, M., Sujith, S., Fernando, Edwin, Srinivasaprasad, N. D., Kurien, Anila Abraham, Raj, T. Yashwanth
• Format: Article
• Language: English
• Subjects: Adult; Anti-Retroviral Agents - therapeutic use; Antibiotics; Antiretroviral Therapy, Highly Active; Apoptosis; Arthralgia; Arthritis; Bacterial infections; Biopsy; Blood; Care and treatment; Case studies; Consent; Cytokines; Diagnosis; Edema; Efavirenz; Female; Health aspects; Highly active antiretroviral therapy; HIV; HIV infections; HIV Infections - complications; HIV Infections - drug therapy; HIV patients; Human immunodeficiency virus; Humans; Immunosuppressive Agents - therapeutic use; Infection; Infections; Kidney diseases; Laboratories; Lupus; Lupus erythematosus; Lupus Nephritis - diagnosis; Lupus Nephritis - drug therapy; Lupus Nephritis - virology; Medical research; Nephritis; Patients; Proteins; Rash; Systemic lupus erythematosus; Ulcers; Urine; التشخيص; التهاب الكلى الذئبي; المرضى; المضاعفات; المواد المضادة للفيروسات القهقرية
• ISSN: 1319-2442; 2320-3838
• DOI: 10.4103/1319-2442.256861

A 38-year-old woman, diagnosed as Person Living with Human Immunodeficiency Virus (HIV) on Highly Active Antiretroviral Therapy (HAART) for three years, presented with features of fever, rashes, joint pain, dyspnea and pedal edema. On evaluation, a diagnosis of Systemic Lupus Erythematosus with Lupus Nephritis (LN) triggered by HIV infection was made based on clinical and serological evidence. She was continued on HAART, and immuno- suppressive therapy was co-administered resulting in the resolution of her symptoms. Lupus-like histopathological findings have been reported in patients with HIV-related kidney diseases. This case report is to highlight the co-existence of LN in a patient with HIV infection.