Electroretinogram Changes Following Sequential Panretinal Photocoagulation for Proliferative Diabetic Retinopathy

To evaluate changes in electroretinogram (ERG) response over the course of multiple sessions of panretinal photocoagulation (PRP) in patients with proliferative diabetic retinopathy (PRP). A prospective cohort study of 11 patients with PDR who required PRP was conducted. PRP was completed over three...

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Bibliographic Details
Published in:Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2020-01, Vol.14, p.967-975
Main Authors: Khojasteh, Hassan, Amini Vishte, Rasoul, Mirzajani, Ali, Khalili Pour, Elias, Bazvand, Fatemeh, Riazi-Esfahani, Hamid, Mirghorbani, Masoud, Modjtahedi, Bobeck S
Format: Article
Language:English
Subjects:
Diabetes
Diabetic retinopathy
electroretinogram
laser
Lasers
Light
Medical research
Original Research
pan-retinal photocoagulation
Patients
Retina
Statistical analysis
Values
Vascular endothelial growth factor
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Summary:To evaluate changes in electroretinogram (ERG) response over the course of multiple sessions of panretinal photocoagulation (PRP) in patients with proliferative diabetic retinopathy (PRP). A prospective cohort study of 11 patients with PDR who required PRP was conducted. PRP was completed over three sessions. Each patient had five ERGs done: baseline, 1 week after each PRP session, and 6 weeks after the last session of PRP. Dark-adapted 0.01 ERG, Dark-adapted 3 ERG, Dark-adapted 10 ERG, Light- adapted 3 ERG, and Light-adapted 30 Hz flicker ERG were done. The mean change in a- and b-wave amplitudes as well as implicit times compared to baseline was analyzed. A significant reduction in peak amplitudes of both a- and b-waves and delay in latencies were observed in all responses (p
ISSN:1177-5467
1177-5483
1177-5483
DOI:10.2147/OPTH.S248678