GC-MS analysis of mango stem bark extracts (Mangifera indica L.), Haden variety. Possible contribution of volatile compounds to its health effects

• Published in: Open Chemistry 2021-01, Vol.19 (1), p.27-38
• Main Authors: Núñez Sellés, Alberto J., Agüero, Juan Agüero, Paz, Lauro Nuevas
• Format: Article
• Language: English
• Subjects: GC-MS; Haden variety; mangifera indica; mango stem bark; preparative column chromatography
• ISSN: 2391-5420; 2391-5420
• DOI: 10.1515/chem-2021-0192

Mango stem bark extracts (MSBE) have been used as bioactive ingredients for nutraceutical, cosmeceutical, and pharmaceutical formulations due to their antioxidant, anti-inflammatory, and analgesic effects. We performed the MSBE preparative column liquid chromatography, which led to the resolution and identification by GC-MS of 64 volatile compounds: 7 hydrocarbons, 3 alcohols, 1 ether, 3 aldehydes/ketones, 7 phenols, 20 terpenoids (hydrocarbons and oxygenated derivatives), 9 steroids, 4 nitrogen compounds, and 1 sulphur compound. Major components were -elemene, -guaiene, aromadendrene, hinesol, 1-octadecene, -eudesmol, methyl linoleate, juniper camphor, hinesol, 9-methyl (3 ,5 )-androstan-3-ol, γ-sitosterol, -chamigrene, 2,5-dihydroxymethyl-phenetylalcohol, -phenyl-2-naphtaleneamine, and several phenolic compounds. The analysis of MSBE, Haden variety, by GC-MS is reported for the first time, which gives an approach to understand the possible synergistic effect of volatile compounds on its antioxidant, analgesic, and anti-inflammatory effects. The identification of relevant bioactive volatile components from MSBE extracts, mainly terpenes from the eudesmane family, will contribute to correlate its chemical composition to previous determined pharmacological effects.