Antibiotic resistance: Evaluation of levofloxacin treatment in acute respiratory tract infections cases at the Tasikmalaya City Health Center, Indonesia

Acute respiratory tract infections (ARTIs) are an acute inflammation of the upper and lower respiratory tract caused by the infection of microorganisms or bacteria, viruses, without or accompanied by inflammation of the lung parenchyma. The use of antibiotics is one way to treat respiratory diseases...

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Bibliographic Details
Published in:Journal of advanced pharmaceutical technology and research 2020-07, Vol.11 (3), p.113-116
Main Authors: Ramdhani, Danni, Azizah, Shinta, Kusuma, Sri, Sediana, Dede
Format: Article
Language:English
Subjects:
acute respiratory tract infections
Analysis
Antibiotic resistance
Antibiotics
Bacteria
Clinical isolates
Conflicts of interest
Drug resistance
Drug therapy
Gram-negative bacteria
Gram-positive bacteria
Health aspects
Identification
Infection
Infections
Lactose
Levofloxacin
Medical research
Microbial drug resistance
Morphology
Mortality
Motility
Original
Parenchyma
Patient compliance
Patients
Physiology
Respiratory diseases
Respiratory tract diseases
Respiratory tract infection
Sensitivity analysis
Streptococcus infections
Urban health
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Summary:Acute respiratory tract infections (ARTIs) are an acute inflammation of the upper and lower respiratory tract caused by the infection of microorganisms or bacteria, viruses, without or accompanied by inflammation of the lung parenchyma. The use of antibiotics is one way to treat respiratory diseases. This study aims to determine the level of resistance of levofloxacin antibiotics to clinical isolates from ARTIs patients at the Tasikmalaya Health Center, Indonesia. The stages of the research included rejuvenation of clinical single isolates from ARTIs patients, identification of bacteria, and antibiotic resistance testing using the paper-disc method. The results of resistance tests from 142 single clinical isolates of acute respiratory infections showed that levofloxacin antibiotics had high levels of resistance of 50.0%, 30.95% of resistance with intermediate levels, and 19.04% were still sensitive. Bacterial identification test results showed bacteria that have been resistant to levofloxacin are from the genus Haemophillus, Streptococcus, Corynebacterium, Staphylococcus, and Bordetella. Treatment of ARTIs with the antibiotic levofloxacin shows that there has been a relatively large resistance, where the results of the identification of all bacteria showed the bacteria that cause ARTIs.
ISSN:2231-4040
0976-2094
DOI:10.4103/japtr.JAPTR_17_20