Erythroderma as first manifestation of squamous cell lung cancer: rare case report

Erythroderma as the first manifestation of a solid organ malignancy is rare. The underlying cancer is a challenging condition to diagnose. There are a few cases of erythroderma in cancer patients reported in the literature. We here describe the case of a 70-year-old man who presented with asthenia,...

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Bibliographic Details
Published in:Anais brasileiros de dermatología 2020-01, Vol.95 (1), p.67-70
Main Authors: Arandes-Marcocci, Jorge, Iglesias-Sancho, Maribel, Setó-Torrent, Núria, Fernández-Figueras, María Teresa
Format: Article
Language:English
Subjects:
Aged
Biopsy
Carcinoma, squamous cell
Case Report
Dermatitis, exfoliative
Dermatitis, Exfoliative - etiology
Dermatitis, Exfoliative - pathology
DERMATOLOGY
Erythema - pathology
Humans
Lung neoplasms
Lung Neoplasms - complications
Lung Neoplasms - pathology
Male
Neoplasms, Squamous Cell - complications
Neoplasms, Squamous Cell - pathology
Paraneoplastic syndromes
Paraneoplastic Syndromes - pathology
Skin diseases
Tomography, X-Ray Computed
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Summary:Erythroderma as the first manifestation of a solid organ malignancy is rare. The underlying cancer is a challenging condition to diagnose. There are a few cases of erythroderma in cancer patients reported in the literature. We here describe the case of a 70-year-old man who presented with asthenia, weight loss, dry cough and total body erythema with desquamation over the past month. A chest computed tomography scan showed a nodular lesion, which was finally diagnosed as a squamous cell lung carcinoma. To our knowledge, as an erythroderma presentation, only 13 cases have been reported in the literature. This case report demonstrates the need to search for a neoplasm in patients presenting with erythroderma, particularly in the presence of accompanying debilitating symptoms.
ISSN:0365-0596
1806-4841
1806-4841
DOI:10.1016/j.abd.2019.05.004