Exploring the relation between the EQ-5D-5L pain/discomfort and pain and itching in a sample of burn patients

The EQ-5D domain pain/discomfort (PD) uses one item to capture pain and other aspects of discomfort, like itching. This study explored how pain, itching and the EQ-5D-5L PD domain relate to each other in a sample of burn patients. Adult burn patients completed the EQ-5D-5L and the Patient and Observ...

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Published in:Health and quality of life outcomes 2020-05, Vol.18 (1), p.144-144, Article 144
Main Authors: Spronk, I, Bonsel, G J, Polinder, S, van Baar, M E, Janssen, M F, Haagsma, J A
Format: Article
Language:English
Subjects:
Activities of daily living
Analysis
Burn patients
Burns
Chronic illnesses
Comorbidity
Correlation coefficient
Correlation coefficients
Discomfort
Disease
Domains
Dutch language
EQ-5D-5L
Health-related quality of life
Hospitals
Itching
Pain
Patients
POSAS
Psoriasis
Quality assessment
Regression analysis
Studies
Variables
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creator Spronk, I
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description The EQ-5D domain pain/discomfort (PD) uses one item to capture pain and other aspects of discomfort, like itching. This study explored how pain, itching and the EQ-5D-5L PD domain relate to each other in a sample of burn patients. Adult burn patients completed the EQ-5D-5L and the Patient and Observer Scar Assessment Scale (POSAS) 5-7 years after sustaining their injury. The POSAS includes a separate pain and an itching item. Spearman's correlation coefficient established the association between the EQ-5D-5L PD and the POSAS pain and itching item. With multivariable regression analysis the linear association between the POSAS pain and itching item and EQ-5D-5L PD domain was tested. Data from 245 patients were included. Mean EQ-5D-5L index value was 0.87 and 39.2% reported at least slight problems on the EQ-5D-5L PD domain. Most patients gave corresponding answers on the EQ-5D-5L PD domain and on the POSAS pain (73%) and itching (70%) item. Spearman correlation coefficients of the EQ-5D-5L PD domain with the POSAS pain and itching were 0.468 (p 
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Among respondents with pain and without itching and respondents with itching and without pain, Spearman correlation coefficients were 0.585 (p = 0.076) and 0.408 (p = 0.001), respectively. POSAS pain (unstandardized Beta = 0.14) and POSAS itching (unstandardized Beta = 0.08) were significantly associated with EQ-5D-5L PD domain (p &lt; 0.001). Our findings indicate that, in a sample of burn patients, pain and itching are captured by the broader EQ-5D-5L PD domain. The EQ-5D-5L PD domain can thus be used to assess pain and itching in relation to HRQL, but the POSAS pain and itching items are more sensitive. The EQ-5D-5L is, however, no replacement of the POSAS when the POSAS is used for its primary aim; assessment of scar quality. 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This study explored how pain, itching and the EQ-5D-5L PD domain relate to each other in a sample of burn patients. Adult burn patients completed the EQ-5D-5L and the Patient and Observer Scar Assessment Scale (POSAS) 5-7 years after sustaining their injury. The POSAS includes a separate pain and an itching item. Spearman's correlation coefficient established the association between the EQ-5D-5L PD and the POSAS pain and itching item. With multivariable regression analysis the linear association between the POSAS pain and itching item and EQ-5D-5L PD domain was tested. Data from 245 patients were included. Mean EQ-5D-5L index value was 0.87 and 39.2% reported at least slight problems on the EQ-5D-5L PD domain. Most patients gave corresponding answers on the EQ-5D-5L PD domain and on the POSAS pain (73%) and itching (70%) item. Spearman correlation coefficients of the EQ-5D-5L PD domain with the POSAS pain and itching were 0.468 (p &lt; 0.001) and 0.473 (p &lt; 0.001), respectively. Among respondents with pain and without itching and respondents with itching and without pain, Spearman correlation coefficients were 0.585 (p = 0.076) and 0.408 (p = 0.001), respectively. POSAS pain (unstandardized Beta = 0.14) and POSAS itching (unstandardized Beta = 0.08) were significantly associated with EQ-5D-5L PD domain (p &lt; 0.001). Our findings indicate that, in a sample of burn patients, pain and itching are captured by the broader EQ-5D-5L PD domain. The EQ-5D-5L PD domain can thus be used to assess pain and itching in relation to HRQL, but the POSAS pain and itching items are more sensitive. The EQ-5D-5L is, however, no replacement of the POSAS when the POSAS is used for its primary aim; assessment of scar quality. 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source Publicly Available Content Database; PubMed Central
subjects Activities of daily living
Analysis
Burn patients
Burns
Chronic illnesses
Comorbidity
Correlation coefficient
Correlation coefficients
Discomfort
Disease
Domains
Dutch language
EQ-5D-5L
Health-related quality of life
Hospitals
Itching
Pain
Patients
POSAS
Psoriasis
Quality assessment
Regression analysis
Studies
Variables
title Exploring the relation between the EQ-5D-5L pain/discomfort and pain and itching in a sample of burn patients
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