Clonal Expansion of Biofilm-Forming Salmonella Typhimurium ST34 with Multidrug-Resistance Phenotype in the Southern Coastal Region of China

• Published in: Frontiers in microbiology 2017-10, Vol.8, p.2090-2090
• Main Authors: Li, Wanli, Li, Yinghui, Liu, Yao, Shi, Xiaolu, Jiang, Min, Lin, Yiman, Qiu, Yaqun, Zhang, Qian, Chen, Qiongcheng, Zhou, Li, Sun, Qun, Hu, Qinghua
• Format: Article
• Language: English
• Subjects: antibiotic resistance; biofilm; genetic diversity; Microbiology; Salmonella Typhimurium; ST34
• ISSN: 1664-302X; 1664-302X
• DOI: 10.3389/fmicb.2017.02090

To disclose the antibiotics susceptibility and wide adaptability of commonly occurring genotypes of Typhimurium, the antibiotic resistance and biofilm formation of different multi-locus sequence typing (MLST) types of a collection of 240 . Typhimurium isolates (33 food and 207 clinical ones) during 2010-2014 in Shenzhen were analyzed. Among these strains, 167 was ST34 (69.58%), and 57 was ST19 (23.75%), respectively. A total of 159 (95.21%) ST34 strains displayed the multidrug resistant phenotype (≥ three classes of antibiotic), whereas only 23 (40.35%) ST19 ones did ( < 0.01). Moreover, a relative high proportion (72.46%) of ST34 isolates was classified as moderate to strong biofilm-producers, while only 15.79% of ST19 ( < 0.01) was. Among the food isolates, more than half (51.52%) were from livestock products, among which 41.18% classified as moderate to strong biofilm-producers. In summary, this study highlights the expansion of . Typhimurium ST34 of strong biofilm-forming ability and multidrug resistance in the southern coastal region of China. Therefore, monitoring the occurrence of ST34 . Typhimurium in food sources, especially in livestock products, and taking appropriate measures to control spp. infections via decreasing biofilm formation should be addressed.