Cauda equina non-Hodgkin lymphoma and literature review: Report of 2 cases

Primary non-Hodgkin's lymphoma (NHL) occurring in the cauda equina region within the spinal canal is exceedingly rare. It is characterized by severe clinical symptoms, a high rate of misdiagnosis, rapid progression, poor prognosis, and significant metastasis potential. In this paper, we report...

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Bibliographic Details
Published in:Radiology case reports 2025-02, Vol.20 (2), p.993-998
Main Authors: Ren, Liliang, Zhang, Shouming, Wang, Aijie, Huang, Ranran, Li, Zhongwei, Zhang, Guowei
Format: Article
Language:English
Subjects:
Case Report
Cauda equina
Lymphoma
Magnetic resonance imaging (MRI)
Spinal canal
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Summary:Primary non-Hodgkin's lymphoma (NHL) occurring in the cauda equina region within the spinal canal is exceedingly rare. It is characterized by severe clinical symptoms, a high rate of misdiagnosis, rapid progression, poor prognosis, and significant metastasis potential. In this paper, we report 1 case of a 58-year-old female with primary NHL and another case of a 69-year-old male with secondary NHL. Both cases exhibited similar MRI findings, presenting the ``cauda equina engulfment'' sign. Early diagnosis and treatment, based on the recognition of these rare imaging features in combination with clinical history and cauda equina histopathological examination, are crucial for improving patient outcomes.
ISSN:1930-0433
1930-0433
DOI:10.1016/j.radcr.2024.10.144