The effects of Alkanna tinctoria Tausch on split-thickness skin graft donor site management: a randomized, blinded placebo-controlled trial

A prospective, randomized, placebo-controlled clinical trial was conducted to compare the healing effectiveness of Alkanna tinctoria (L.) Tausch (Boraginaceae) with standard dressing on wound healing at the donor site after removal of the skin graft. Enrolled patients were randomly allocated to rece...

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Bibliographic Details
Published in:BMC complementary and alternative medicine 2017-05, Vol.17 (1), p.253-253, Article 253
Main Authors: Kheiri, Aliasghar, Amini, Shahideh, Javidan, Abbas Norouzi, Saghafi, Mohammad Mehdi, Khorasani, Ghasemali
Format: Article
Language:English
Subjects:
Adult
Alkanna
Boraginaceae - chemistry
Clinical trials
Edema
Evidence-based medicine
Female
Grafting
Healing
Humans
Inflammation
Intervention
Knee
Laboratory animals
Male
Management
Middle Aged
Ointments
Patients
Plant Extracts - administration & dosage
Plastic surgery
Prospective Studies
Researchers
Skin
Skin & tissue grafts
Skin Diseases - physiopathology
Skin Diseases - surgery
Skin graft
Skin grafts
Skin Transplantation
Wound
Wound healing
Wound Healing - drug effects
Young Adult
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Summary:A prospective, randomized, placebo-controlled clinical trial was conducted to compare the healing effectiveness of Alkanna tinctoria (L.) Tausch (Boraginaceae) with standard dressing on wound healing at the donor site after removal of the skin graft. Enrolled patients were randomly allocated to receive topicalA. tinctoria extract ointment (20%) or standard dressing (dressing with base ointment) daily. Wound healing was assessed using the Bates-Jenson assessment tool at the 2 and 4 weeks after intervention. Decreases in wound score were significantly greater in the A. tinctoria group compared with the placebo group (P
ISSN:1472-6882
1472-6882
DOI:10.1186/s12906-017-1741-0