Ischaemic stroke etiological classification system: the agreement analysis of CISS, SPARKLE and TOAST

Background and purposeThe ideal stroke classification system needs to have validity, high reliability and applicability among different stroke research settings. The Chinese Ischemic Stroke Subclassification (CISS) and the Subtypes of Ischemic Stroke Classification System (SPARKLE) have emerged rece...

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Bibliographic Details
Published in:Stroke and vascular neurology 2019-09, Vol.4 (3), p.123-128
Main Authors: Zhang, Haojie, Li, Zixiao, Dai, Yunyi, Guo, Enhui, Zhang, Changqing, Wang, Yongjun
Format: Article
Language:English
Subjects:
Aged
Atherosclerosis
Beijing
Cardiac arrhythmia
Cardiovascular disease
Classification
classification system
Decision Support Techniques
Diabetes
Etiology
Female
Heart attacks
Humans
Hypertension
ischemic stroke
Ischemic Stroke - classification
Ischemic Stroke - diagnosis
Ischemic Stroke - etiology
Male
Medical imaging
Middle Aged
Normal distribution
Observer Variation
Original
Original article
Patients
Predictive Value of Tests
Reproducibility of Results
Retrospective Studies
Risk Assessment
Risk Factors
Smoking
Statistical analysis
Stroke
Terminology as Topic
Ultrasonic imaging
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Summary:Background and purposeThe ideal stroke classification system needs to have validity, high reliability and applicability among different stroke research settings. The Chinese Ischemic Stroke Subclassification (CISS) and the Subtypes of Ischemic Stroke Classification System (SPARKLE) have emerged recently but have not been tested using agreement analysis. As a result, the objective of this study is to investigate the level of agreement among stroke subtype classifications using CISS, SPARKLE and Trial of Org 10172 in Acute Stroke Treatment (TOAST). We also analyse the inter-rater reliability of CISS.MethodsThe data include 623 inpatients who have had an ischaemic stroke, accrued from Beijing Tiantan Hospital between 1 October 2015 and 19 April 2016. According to the diagnostic standards of the three subtype classification systems, 299 inpatients who satisfied the requirements of our study were independently classified with etiological subtypes, and we compared the three subclassifications.ResultsThere was substantial overall agreement among the three classification systems: CISS versus SPARKLE (kappa value=0.684, p
ISSN:2059-8688
2059-8696
DOI:10.1136/svn-2018-000226