Generation of a human induced pluripotent stem cell line (OGIi001) from peripheral blood mononuclear cells of a healthy male donor

We have successfully derived a novel human induced pluripotent stem cell (hiPSC) line using non-integrative Sendai virus. This hiPSC line was generated from a healthy male adult donor, aged 55, and subjected to thorough characterization and extensive quality control. The analysis confirmed the expre...

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Bibliographic Details
Published in:Stem cell research 2024-02, Vol.74, p.103280-103280, Article 103280
Main Authors: Zhang, Hanmeng, Daheron, Laurence, Cerna-Chavez, Rodrigo, Place, Emily M., Huckfeldt, Rachel M., Pierce, Eric A., Garita-Hernandez, Marcela
Format: Article
Language:English
Subjects:
Adult
Cell Differentiation
Cell Line
Cellular Reprogramming
Chromosome Aberrations
Humans
Induced Pluripotent Stem Cells - metabolism
Leukocytes, Mononuclear - metabolism
Male
Sendai virus - genetics
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Summary:We have successfully derived a novel human induced pluripotent stem cell (hiPSC) line using non-integrative Sendai virus. This hiPSC line was generated from a healthy male adult donor, aged 55, and subjected to thorough characterization and extensive quality control. The analysis confirmed the expression of undifferentiated stem cell markers, demonstrated the ability to differentiate into the three germ layers, and revealed the absence of any chromosomal abnormalities.
ISSN:1873-5061
1876-7753
1876-7753
DOI:10.1016/j.scr.2023.103280