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Malignant Arrhythmias as the Unmasked Manifestation of Thyroid Storm
Thyroid storm is usually due to a severe exacerbation of a preexisting thyrotoxicosis, which later leads to decompensation in different organ systems. Thyroid storm with malignant arrhythmia is rare, but the mortality rate is high. Malignant arrhythmia has usually occurred in some patients with hypo...
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Published in: | International journal of general medicine 2020-09, Vol.13, p.693-698 |
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description | Thyroid storm is usually due to a severe exacerbation of a preexisting thyrotoxicosis, which later leads to decompensation in different organ systems. Thyroid storm with malignant arrhythmia is rare, but the mortality rate is high. Malignant arrhythmia has usually occurred in some patients with hypokalemia or ischemic heart disease. The presentation of these arrhythmias in the initial phase of the disease is much less common, and only a few isolated cases are described in the scientific literature. This paper analyzes and summarizes the clinical characteristics of this disease through literature reviews, for clinicians early detection and diagnosis of this disease. We report a 51-year-old woman with diarrhoea, fever, thyroid storm, ventricular fibrillation and no potential heart disease. The case report is discussed using relevant data from literature. A total of 9 patients were reported in the literature, totalling 10 cases with ours, including 7 cases of ventricular fibrillation and 3 cases of ventricular tachycardia. Most of the treatments were antithyroid drugs, hormones and beta-receptor blockers, and 3 death cases. Patients with thyroid crisis need to be closely monitored for malignant arrhythmias. Early diagnosis and treatment may save lives. Keywords: thyroid storm, malignant arrhythmia, ventricular tachycardia |
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Thyroid storm with malignant arrhythmia is rare, but the mortality rate is high. Malignant arrhythmia has usually occurred in some patients with hypokalemia or ischemic heart disease. The presentation of these arrhythmias in the initial phase of the disease is much less common, and only a few isolated cases are described in the scientific literature. This paper analyzes and summarizes the clinical characteristics of this disease through literature reviews, for clinicians early detection and diagnosis of this disease. We report a 51-year-old woman with diarrhoea, fever, thyroid storm, ventricular fibrillation and no potential heart disease. The case report is discussed using relevant data from literature. A total of 9 patients were reported in the literature, totalling 10 cases with ours, including 7 cases of ventricular fibrillation and 3 cases of ventricular tachycardia. Most of the treatments were antithyroid drugs, hormones and beta-receptor blockers, and 3 death cases. Patients with thyroid crisis need to be closely monitored for malignant arrhythmias. Early diagnosis and treatment may save lives. Keywords: thyroid storm, malignant arrhythmia, ventricular tachycardia</description><identifier>ISSN: 1178-7074</identifier><identifier>EISSN: 1178-7074</identifier><identifier>DOI: 10.2147/IJGM.S265833</identifier><identifier>PMID: 33061537</identifier><language>eng</language><publisher>Macclesfield: Dove Medical Press Limited</publisher><subject>Age ; Analysis ; Antibodies ; Beta blockers ; Cardiac arrhythmia ; Cardiovascular disease ; Case Report ; Consciousness ; Consent ; Diagnosis ; Drugs ; Electrocardiography ; Enzymes ; Fever ; Health aspects ; Heart ; Heart failure ; Heart rate ; Hyperthyroidism ; Infections ; Ischemia ; Laboratories ; Mortality ; Patients ; Tachycardia ; Thyroid diseases ; Thyroid gland ; thyroid storm·malignantarrhythmia·ventricular tachycardia</subject><ispartof>International journal of general medicine, 2020-09, Vol.13, p.693-698</ispartof><rights>COPYRIGHT 2020 Dove Medical Press Limited</rights><rights>2020. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2020 Shang and Ma. 2020 Shang and Ma.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c520t-958c9962f3dd8222d95c933813342cc93f0bac50075206e55d4c307f622570bb3</citedby><cites>FETCH-LOGICAL-c520t-958c9962f3dd8222d95c933813342cc93f0bac50075206e55d4c307f622570bb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2451487459/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2451487459?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,44590,53791,53793,75126</link.rule.ids></links><search><creatorcontrib>Shang, Wen</creatorcontrib><creatorcontrib>Ma, Qing-Bian</creatorcontrib><title>Malignant Arrhythmias as the Unmasked Manifestation of Thyroid Storm</title><title>International journal of general medicine</title><description>Thyroid storm is usually due to a severe exacerbation of a preexisting thyrotoxicosis, which later leads to decompensation in different organ systems. Thyroid storm with malignant arrhythmia is rare, but the mortality rate is high. Malignant arrhythmia has usually occurred in some patients with hypokalemia or ischemic heart disease. The presentation of these arrhythmias in the initial phase of the disease is much less common, and only a few isolated cases are described in the scientific literature. This paper analyzes and summarizes the clinical characteristics of this disease through literature reviews, for clinicians early detection and diagnosis of this disease. We report a 51-year-old woman with diarrhoea, fever, thyroid storm, ventricular fibrillation and no potential heart disease. The case report is discussed using relevant data from literature. A total of 9 patients were reported in the literature, totalling 10 cases with ours, including 7 cases of ventricular fibrillation and 3 cases of ventricular tachycardia. Most of the treatments were antithyroid drugs, hormones and beta-receptor blockers, and 3 death cases. Patients with thyroid crisis need to be closely monitored for malignant arrhythmias. Early diagnosis and treatment may save lives. Keywords: thyroid storm, malignant arrhythmia, ventricular tachycardia</description><subject>Age</subject><subject>Analysis</subject><subject>Antibodies</subject><subject>Beta blockers</subject><subject>Cardiac arrhythmia</subject><subject>Cardiovascular disease</subject><subject>Case Report</subject><subject>Consciousness</subject><subject>Consent</subject><subject>Diagnosis</subject><subject>Drugs</subject><subject>Electrocardiography</subject><subject>Enzymes</subject><subject>Fever</subject><subject>Health aspects</subject><subject>Heart</subject><subject>Heart failure</subject><subject>Heart rate</subject><subject>Hyperthyroidism</subject><subject>Infections</subject><subject>Ischemia</subject><subject>Laboratories</subject><subject>Mortality</subject><subject>Patients</subject><subject>Tachycardia</subject><subject>Thyroid diseases</subject><subject>Thyroid gland</subject><subject>thyroid storm·malignantarrhythmia·ventricular tachycardia</subject><issn>1178-7074</issn><issn>1178-7074</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptkl2LEzEUhgdR3A-98wcMCF7Zmu9kboSy666VLV7s7nXI5KOTOpOsSSr035vaoluQBHI4ec_DOcnbNO8gmCNI-Kflt9vV_B4xKjB-0ZxDyMWMA05ePovPmoucNwAwxiB-3ZxhDBikmJ831ys1-nVQobSLlIZdGSavclt3GWz7GCaVf1jTrlTwzuaiio-hja59GHYpetPel5imN80rp8Zs3x7Py-bx5svD1dfZ3ffb5dXibqYpAmXWUaG7jiGHjREIIdNR3WEsIMYE6Ro60CtNAeBVziylhmgMuGMIUQ76Hl82ywPXRLWRT8lPKu1kVF7-ScS0lioVr0criRFYOM76XiMCuFVUQSFABbmeMoIq6_OB9bTtJ2u0DSWp8QR6ehP8INfxl6zNIQL3gPdHQIo_t_Vt5CZuU6jzS0QoJIIT2v1TrVXtygcXK0xPPmu5YFgIwjoMqmr-H1Vdxk5ex2Cdr_mTgg_PCgarxjLkOG7335NPhR8PQp1izsm6vxNCIPf-kXv_yKN_8G9a6rLL</recordid><startdate>20200930</startdate><enddate>20200930</enddate><creator>Shang, Wen</creator><creator>Ma, Qing-Bian</creator><general>Dove Medical Press Limited</general><general>Taylor & Francis Ltd</general><general>Dove</general><general>Dove Medical Press</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20200930</creationdate><title>Malignant Arrhythmias as the Unmasked Manifestation of Thyroid Storm</title><author>Shang, Wen ; Ma, Qing-Bian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c520t-958c9962f3dd8222d95c933813342cc93f0bac50075206e55d4c307f622570bb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>Age</topic><topic>Analysis</topic><topic>Antibodies</topic><topic>Beta blockers</topic><topic>Cardiac arrhythmia</topic><topic>Cardiovascular disease</topic><topic>Case Report</topic><topic>Consciousness</topic><topic>Consent</topic><topic>Diagnosis</topic><topic>Drugs</topic><topic>Electrocardiography</topic><topic>Enzymes</topic><topic>Fever</topic><topic>Health aspects</topic><topic>Heart</topic><topic>Heart failure</topic><topic>Heart rate</topic><topic>Hyperthyroidism</topic><topic>Infections</topic><topic>Ischemia</topic><topic>Laboratories</topic><topic>Mortality</topic><topic>Patients</topic><topic>Tachycardia</topic><topic>Thyroid diseases</topic><topic>Thyroid gland</topic><topic>thyroid storm·malignantarrhythmia·ventricular tachycardia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shang, Wen</creatorcontrib><creatorcontrib>Ma, Qing-Bian</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest research library</collection><collection>Research Library (Corporate)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>International journal of general medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shang, Wen</au><au>Ma, Qing-Bian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Malignant Arrhythmias as the Unmasked Manifestation of Thyroid Storm</atitle><jtitle>International journal of general medicine</jtitle><date>2020-09-30</date><risdate>2020</risdate><volume>13</volume><spage>693</spage><epage>698</epage><pages>693-698</pages><issn>1178-7074</issn><eissn>1178-7074</eissn><abstract>Thyroid storm is usually due to a severe exacerbation of a preexisting thyrotoxicosis, which later leads to decompensation in different organ systems. Thyroid storm with malignant arrhythmia is rare, but the mortality rate is high. Malignant arrhythmia has usually occurred in some patients with hypokalemia or ischemic heart disease. The presentation of these arrhythmias in the initial phase of the disease is much less common, and only a few isolated cases are described in the scientific literature. This paper analyzes and summarizes the clinical characteristics of this disease through literature reviews, for clinicians early detection and diagnosis of this disease. We report a 51-year-old woman with diarrhoea, fever, thyroid storm, ventricular fibrillation and no potential heart disease. The case report is discussed using relevant data from literature. A total of 9 patients were reported in the literature, totalling 10 cases with ours, including 7 cases of ventricular fibrillation and 3 cases of ventricular tachycardia. Most of the treatments were antithyroid drugs, hormones and beta-receptor blockers, and 3 death cases. Patients with thyroid crisis need to be closely monitored for malignant arrhythmias. Early diagnosis and treatment may save lives. Keywords: thyroid storm, malignant arrhythmia, ventricular tachycardia</abstract><cop>Macclesfield</cop><pub>Dove Medical Press Limited</pub><pmid>33061537</pmid><doi>10.2147/IJGM.S265833</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Age Analysis Antibodies Beta blockers Cardiac arrhythmia Cardiovascular disease Case Report Consciousness Consent Diagnosis Drugs Electrocardiography Enzymes Fever Health aspects Heart Heart failure Heart rate Hyperthyroidism Infections Ischemia Laboratories Mortality Patients Tachycardia Thyroid diseases Thyroid gland thyroid storm·malignantarrhythmia·ventricular tachycardia |
title | Malignant Arrhythmias as the Unmasked Manifestation of Thyroid Storm |
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