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Aquaporin-5 Dynamic Regulation
Aquaporin-5 (AQP5), belonging to the aquaporins (AQPs) family of transmembrane water channels, facilitates osmotically driven water flux across biological membranes and the movement of hydrogen peroxide and CO . Various mechanisms have been shown to dynamically regulate AQP5 expression, trafficking,...
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| Published in: | International journal of molecular sciences 2023-01, Vol.24 (3), p.1889 |
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| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c478t-1ba5debde08f9f2f44de8972f449f745b701b2a02e30ea6f23e058c0fee3596c3 |
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| cites | cdi_FETCH-LOGICAL-c478t-1ba5debde08f9f2f44de8972f449f745b701b2a02e30ea6f23e058c0fee3596c3 |
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| container_issue | 3 |
| container_start_page | 1889 |
| container_title | International journal of molecular sciences |
| container_volume | 24 |
| creator | D'Agostino, Claudia Parisis, Dorian Chivasso, Clara Hajiabbas, Maryam Soyfoo, Muhammad Shahnawaz Delporte, Christine |
| description | Aquaporin-5 (AQP5), belonging to the aquaporins (AQPs) family of transmembrane water channels, facilitates osmotically driven water flux across biological membranes and the movement of hydrogen peroxide and CO
. Various mechanisms have been shown to dynamically regulate AQP5 expression, trafficking, and function. Besides fulfilling its primary water permeability function, AQP5 has been shown to regulate downstream effectors playing roles in various cellular processes. This review provides a comprehensive overview of the current knowledge of the upstream and downstream effectors of AQP5 to gain an in-depth understanding of the physiological and pathophysiological processes involving AQP5. |
| doi_str_mv | 10.3390/ijms24031889 |
| format | article |
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| ispartof | International journal of molecular sciences, 2023-01, Vol.24 (3), p.1889 |
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| source | Open Access: PubMed Central; Publicly Available Content Database |
| subjects | aquaporin Aquaporin 5 Aquaporin 5 - genetics Aquaporin 5 - metabolism Aquaporins Aquaporins - metabolism Blood & organ donations Carbon dioxide Cell Membrane - metabolism Effectors function Growth hormones Hydrogen peroxide mammalian Mutation Ovaries Permeability Physiology Polymorphism Proteins regulation Respiratory distress syndrome Review Sepsis Steroids trafficking Transcription factors Uterus Water - metabolism |
| title | Aquaporin-5 Dynamic Regulation |
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