Long Noncoding RNAs in Ovarian Cancer-Functions and Clinical Applications

Long noncoding RNAs (lncRNAs) are RNA molecules with a length of more than 200 nt that have been discovered in recent years. LncRNAs can participate in regulating gene expression and various biological activities through multiple pathways, such as at the epigenetic level, transcriptional level, and...

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Bibliographic Details
Published in:Frontiers in bioscience (Landmark. Print) 2023-04, Vol.28 (4), p.71-71
Main Authors: Zhong, Lili, Li, Xin, Wang, Yicun, Liu, Bin, Ding, Xiangfu, Zhao, Yinlong
Format: Article
Language:English
Subjects:
Clinical Relevance
diagnosis
Epigenomics
expression disorder
Female
Gene Expression Regulation, Neoplastic
Humans
long noncoding rnas
ovarian cancer
Ovarian Neoplasms - genetics
Ovarian Neoplasms - metabolism
prognosis
RNA, Long Noncoding - genetics
RNA, Long Noncoding - metabolism
therapy
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Description
Summary:Long noncoding RNAs (lncRNAs) are RNA molecules with a length of more than 200 nt that have been discovered in recent years. LncRNAs can participate in regulating gene expression and various biological activities through multiple pathways, such as at the epigenetic level, transcriptional level, and posttranscriptional level. In recent years, with the increasing understanding of lncRNAs, a large number of studies have shown that lncRNAs are closely related to ovarian cancer and participate in its occurrence and development, providing a new method to investigate ovarian cancer. In this review, we analyzed and summarized the relationship between various lncRNAs and ovarian cancer in terms of occurrence, development, and clinical significance, in order to provide a theoretical basis for basic research and clinical application of ovarian cancer.
ISSN:2768-6701
2768-6698
DOI:10.31083/j.fbl2804071