Role of vitamin e in prevention of oral cancer:-a review

Oral cancer is one of the major global threads to public health. The development of oral cancer is tobacco related mainly. Vitamin-E can inhibit reaction of the tobacco specific nitrosamine which undergoes specific activation, detoxification process. Dietary substitute such as vitamin-E can prevent...

Full description

Saved in:
Bibliographic Details
Published in:Journal of clinical and diagnostic research 2014-10, Vol.8 (10), p.ZE05-ZE07
Main Authors: Iqubal, Md Asad, Khan, Mobeen, Kumar, Prabhakar, Kumar, Anjani, Ajai, Kratika
Format: Article
Language:English
Subjects:
free radicals
oral cancer
premalignant lesions and premalignant conditions
vitamin-e
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Oral cancer is one of the major global threads to public health. The development of oral cancer is tobacco related mainly. Vitamin-E can inhibit reaction of the tobacco specific nitrosamine which undergoes specific activation, detoxification process. Dietary substitute such as vitamin-E can prevent oral cancer at a very early stage that is in premalignant lesions, in premalignant conditions. Main action of vitamin E includes increase immunity, controls free radicals mediated cell disturbances, maintains membrane integrity, inhibit cancer cell growth, cytotoxicity. Many past studies suggest the role of antioxidant (vitamin-E) in treatment of oral mucosal lesions particularly includes oral leukoplakia, oral lichen planus, oral submucous fibrosis and oral cancer. Vitamin-E as an antioxidant helps in prevention and slow the growth of Head and Neck cancer, improve the effects of cancer chemotherapy and reduce the side effects from both chemotherapy and radiation therapy for cancer patients. As prevention modality use of Vitamin-E may be beneficial for human beings.
ISSN:2249-782X
0973-709X
DOI:10.7860/JCDR/2014/9166.4958