The crosstalk of intratumor bacteria and the tumor

The in-depth studies reveal the interaction between the host and commensal microbiomes. Symbiotic bacteria influence in tumor initiation, progression, and response to treatment. Recently, intratumor bacteria have been a burgeoning research field. The tumor microenvironment is under vascular hyperpla...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in cellular and infection microbiology 2024-01, Vol.13, p.1273254-1273254
Main Authors: Huang, Jiating, Mao, Yuqin, Wang, Lishun
Format: Article
Language:English
Subjects:
bacteria
Cellular and Infection Microbiology
immune
intratumor
therapy
tumor
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c420t-f006c8e3a05a9b9e2da36175812a027062ff4d8ca31f5d11d62acf7404fa66c3
container_end_page 1273254
container_issue
container_start_page 1273254
container_title Frontiers in cellular and infection microbiology
container_volume 13
creator Huang, Jiating
Mao, Yuqin
Wang, Lishun
description The in-depth studies reveal the interaction between the host and commensal microbiomes. Symbiotic bacteria influence in tumor initiation, progression, and response to treatment. Recently, intratumor bacteria have been a burgeoning research field. The tumor microenvironment is under vascular hyperplasia, aerobic glycolysis, hypoxia, and immunosuppression. It might be attractive for bacterial growth and proliferation. As a component of the tumor microenvironment, intratumor bacteria influence tumor growth and metastasis, as well as the efficacy of anti-tumor therapies. Therefore, understanding the intricate interplay of intratumoral bacteria and the host might contribute to better approaches to treat tumors. In this review, we summarize current evidence about roles of intratumor bacteria in tumor initiation and anti-tumor therapy, and what is remained to be solved in this field.
doi_str_mv 10.3389/fcimb.2023.1273254
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_4e2692db83034ccc94302b662e496299</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_4e2692db83034ccc94302b662e496299</doaj_id><sourcerecordid>2916409524</sourcerecordid><originalsourceid>FETCH-LOGICAL-c420t-f006c8e3a05a9b9e2da36175812a027062ff4d8ca31f5d11d62acf7404fa66c3</originalsourceid><addsrcrecordid>eNpVkU1PwzAMhiMEYtPgD3BAPXLZcJw0TU4IIb4kJC67R26aQKFdRtoh8e_pPphGLo7s148Tv4xdcJgJoc11cHVbzhBQzDgWAnN5xMaIIp-i0fr44D5i5133AcMpALURp2wk9FCUBsYM5-8-cyl2XU_NZxZDVi_6RP2qjSkryfU-1ZTRosr6QbhJn7GTQE3nz3dxwuYP9_O7p-nL6-Pz3e3L1EmEfhoAlNNeEORkSuOxIqF4kWuOBFiAwhBkpR0JHvKK80ohuVBIkIGUcmLCnrfYKtKHXaa6pfRjI9V2k4jpzVLqa9d4Kz0qg1WpBQjpnDNSAJZKoZdGoTED62bLWq7K1lfOr__Y_IP-ryzqd_sWvy2HwnAN-UC42hFS_Fr5rrdt3TnfNLTwcdVZNFxJMDnKQYpb6WatyYf9HA527Z3deGfX3tmdd0PT5eEL9y1_TolfNQuUuw</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2916409524</pqid></control><display><type>article</type><title>The crosstalk of intratumor bacteria and the tumor</title><source>PubMed Central(OpenAccess)</source><creator>Huang, Jiating ; Mao, Yuqin ; Wang, Lishun</creator><creatorcontrib>Huang, Jiating ; Mao, Yuqin ; Wang, Lishun</creatorcontrib><description>The in-depth studies reveal the interaction between the host and commensal microbiomes. Symbiotic bacteria influence in tumor initiation, progression, and response to treatment. Recently, intratumor bacteria have been a burgeoning research field. The tumor microenvironment is under vascular hyperplasia, aerobic glycolysis, hypoxia, and immunosuppression. It might be attractive for bacterial growth and proliferation. As a component of the tumor microenvironment, intratumor bacteria influence tumor growth and metastasis, as well as the efficacy of anti-tumor therapies. Therefore, understanding the intricate interplay of intratumoral bacteria and the host might contribute to better approaches to treat tumors. In this review, we summarize current evidence about roles of intratumor bacteria in tumor initiation and anti-tumor therapy, and what is remained to be solved in this field.</description><identifier>ISSN: 2235-2988</identifier><identifier>EISSN: 2235-2988</identifier><identifier>DOI: 10.3389/fcimb.2023.1273254</identifier><identifier>PMID: 38235490</identifier><language>eng</language><publisher>Switzerland: Frontiers Media S.A</publisher><subject>bacteria ; Cellular and Infection Microbiology ; immune ; intratumor ; therapy ; tumor</subject><ispartof>Frontiers in cellular and infection microbiology, 2024-01, Vol.13, p.1273254-1273254</ispartof><rights>Copyright © 2024 Huang, Mao and Wang.</rights><rights>Copyright © 2024 Huang, Mao and Wang 2024 Huang, Mao and Wang</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c420t-f006c8e3a05a9b9e2da36175812a027062ff4d8ca31f5d11d62acf7404fa66c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10791805/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10791805/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38235490$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Huang, Jiating</creatorcontrib><creatorcontrib>Mao, Yuqin</creatorcontrib><creatorcontrib>Wang, Lishun</creatorcontrib><title>The crosstalk of intratumor bacteria and the tumor</title><title>Frontiers in cellular and infection microbiology</title><addtitle>Front Cell Infect Microbiol</addtitle><description>The in-depth studies reveal the interaction between the host and commensal microbiomes. Symbiotic bacteria influence in tumor initiation, progression, and response to treatment. Recently, intratumor bacteria have been a burgeoning research field. The tumor microenvironment is under vascular hyperplasia, aerobic glycolysis, hypoxia, and immunosuppression. It might be attractive for bacterial growth and proliferation. As a component of the tumor microenvironment, intratumor bacteria influence tumor growth and metastasis, as well as the efficacy of anti-tumor therapies. Therefore, understanding the intricate interplay of intratumoral bacteria and the host might contribute to better approaches to treat tumors. In this review, we summarize current evidence about roles of intratumor bacteria in tumor initiation and anti-tumor therapy, and what is remained to be solved in this field.</description><subject>bacteria</subject><subject>Cellular and Infection Microbiology</subject><subject>immune</subject><subject>intratumor</subject><subject>therapy</subject><subject>tumor</subject><issn>2235-2988</issn><issn>2235-2988</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>DOA</sourceid><recordid>eNpVkU1PwzAMhiMEYtPgD3BAPXLZcJw0TU4IIb4kJC67R26aQKFdRtoh8e_pPphGLo7s148Tv4xdcJgJoc11cHVbzhBQzDgWAnN5xMaIIp-i0fr44D5i5133AcMpALURp2wk9FCUBsYM5-8-cyl2XU_NZxZDVi_6RP2qjSkryfU-1ZTRosr6QbhJn7GTQE3nz3dxwuYP9_O7p-nL6-Pz3e3L1EmEfhoAlNNeEORkSuOxIqF4kWuOBFiAwhBkpR0JHvKK80ohuVBIkIGUcmLCnrfYKtKHXaa6pfRjI9V2k4jpzVLqa9d4Kz0qg1WpBQjpnDNSAJZKoZdGoTED62bLWq7K1lfOr__Y_IP-ryzqd_sWvy2HwnAN-UC42hFS_Fr5rrdt3TnfNLTwcdVZNFxJMDnKQYpb6WatyYf9HA527Z3deGfX3tmdd0PT5eEL9y1_TolfNQuUuw</recordid><startdate>20240103</startdate><enddate>20240103</enddate><creator>Huang, Jiating</creator><creator>Mao, Yuqin</creator><creator>Wang, Lishun</creator><general>Frontiers Media S.A</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20240103</creationdate><title>The crosstalk of intratumor bacteria and the tumor</title><author>Huang, Jiating ; Mao, Yuqin ; Wang, Lishun</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c420t-f006c8e3a05a9b9e2da36175812a027062ff4d8ca31f5d11d62acf7404fa66c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>bacteria</topic><topic>Cellular and Infection Microbiology</topic><topic>immune</topic><topic>intratumor</topic><topic>therapy</topic><topic>tumor</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Huang, Jiating</creatorcontrib><creatorcontrib>Mao, Yuqin</creatorcontrib><creatorcontrib>Wang, Lishun</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Open Access: DOAJ - Directory of Open Access Journals</collection><jtitle>Frontiers in cellular and infection microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Huang, Jiating</au><au>Mao, Yuqin</au><au>Wang, Lishun</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The crosstalk of intratumor bacteria and the tumor</atitle><jtitle>Frontiers in cellular and infection microbiology</jtitle><addtitle>Front Cell Infect Microbiol</addtitle><date>2024-01-03</date><risdate>2024</risdate><volume>13</volume><spage>1273254</spage><epage>1273254</epage><pages>1273254-1273254</pages><issn>2235-2988</issn><eissn>2235-2988</eissn><abstract>The in-depth studies reveal the interaction between the host and commensal microbiomes. Symbiotic bacteria influence in tumor initiation, progression, and response to treatment. Recently, intratumor bacteria have been a burgeoning research field. The tumor microenvironment is under vascular hyperplasia, aerobic glycolysis, hypoxia, and immunosuppression. It might be attractive for bacterial growth and proliferation. As a component of the tumor microenvironment, intratumor bacteria influence tumor growth and metastasis, as well as the efficacy of anti-tumor therapies. Therefore, understanding the intricate interplay of intratumoral bacteria and the host might contribute to better approaches to treat tumors. In this review, we summarize current evidence about roles of intratumor bacteria in tumor initiation and anti-tumor therapy, and what is remained to be solved in this field.</abstract><cop>Switzerland</cop><pub>Frontiers Media S.A</pub><pmid>38235490</pmid><doi>10.3389/fcimb.2023.1273254</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2235-2988
ispartof Frontiers in cellular and infection microbiology, 2024-01, Vol.13, p.1273254-1273254
issn 2235-2988
2235-2988
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_4e2692db83034ccc94302b662e496299
source PubMed Central(OpenAccess)
subjects bacteria
Cellular and Infection Microbiology
immune
intratumor
therapy
tumor
title The crosstalk of intratumor bacteria and the tumor
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T05%3A31%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20crosstalk%20of%20intratumor%20bacteria%20and%20the%20tumor&rft.jtitle=Frontiers%20in%20cellular%20and%20infection%20microbiology&rft.au=Huang,%20Jiating&rft.date=2024-01-03&rft.volume=13&rft.spage=1273254&rft.epage=1273254&rft.pages=1273254-1273254&rft.issn=2235-2988&rft.eissn=2235-2988&rft_id=info:doi/10.3389/fcimb.2023.1273254&rft_dat=%3Cproquest_doaj_%3E2916409524%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c420t-f006c8e3a05a9b9e2da36175812a027062ff4d8ca31f5d11d62acf7404fa66c3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2916409524&rft_id=info:pmid/38235490&rfr_iscdi=true