A Challenge of COVID-19: Associated Infective Endocarditis with Streptococcus gordonii in a Young Immunocompetent Patient

The COVID-19 pandemic is a new challenge for the diagnosis and treatment of infective endocarditis (IE). Fever and other unspecific symptoms of coronaviral infection could be misleading or masking its manifestations. We present the case of a young patient admitted for persistent fever, profuse sweat...

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Bibliographic Details
Published in:Medicina (Kaunas, Lithuania) Lithuania), 2021-11, Vol.57 (12), p.1298
Main Authors: Arbune, Manuela, Iancu, Alina-Viorica, Lupasteanu, Gabriela, Vasile, Mihaela-Camelia, Stefanescu, Victorita
Format: Article
Language:English
Subjects:
Antibiotics
Cardiology
Case Report
Coronaviruses
COVID-19
Endocarditis
Endocarditis - diagnosis
Endocarditis - drug therapy
Etiology
Female
Fever
Funding
Heart
Hospitals
Humans
Immunocompetence
Infections
Infectious diseases
infectious endocarditis
Medical research
oral microbiome
Pain
Pandemics
Patients
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Streptococcus gordonii
Systematic review
Thromboembolism
Ultrasonic imaging
Vegetation
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Summary:The COVID-19 pandemic is a new challenge for the diagnosis and treatment of infective endocarditis (IE). Fever and other unspecific symptoms of coronaviral infection could be misleading or masking its manifestations. We present the case of a young patient admitted for persistent fever, profuse sweating, headache, articular pain, myalgias, and weight loss. She reported regression taste and smell disorders compared to a month earlier when diagnosed with moderate COVID-19 pneumonia. While the RT-PCR SARS-COV-2 test was positive, she was admitted to a COVID-19 ward. Investigations of febrile syndrome revealed two positive blood cultures with and the presence of vegetations on the aortic valve, supporting a certain diagnosis of IE. After six weeks of antibiotic treatment, the patient had clinical and biologic favorable outcomes. is a common commensal related to the dental biofilm, although there were no caries in our patient. The influence of COVID-19 infection on the human microbiome by modifying the virulence of some commensal germs may be a risk factor for IE pathogenesis on native valves and requires the vigilance of clinicians for suspicion of this disease.
ISSN:1648-9144
1010-660X
1648-9144
DOI:10.3390/medicina57121298