Volumetric capnography for the evaluation of chronic airways diseases

Obstructive lung diseases of different etiologies present with progressive peripheral airway involvement. The peripheral airways, known as the silent lung zone, are not adequately evaluated with conventional function tests. The principle of gas washout has been used to detect pulmonary ventilation i...

Full description

Saved in:
Bibliographic Details
Published in:International journal of chronic obstructive pulmonary disease 2014-01, Vol.9 (default), p.983-989
Main Authors: Veronez, Liliani, Pereira, Monica Corso, da Silva, Silvia Maria Doria, Barcaui, Luisa Affi, De Capitani, Eduardo Mello, Moreira, Marcos Mello, Paschoal, Ilma Aparecida
Format: Article
Language:English
Subjects:
Adult
Body mass index
Brazil
Bronchiectasis - diagnosis
Bronchiectasis - physiopathology
Bronchitis - diagnosis
Bronchitis - physiopathology
Capnography
Case-Control Studies
Chronic obstructive pulmonary disease
Cystic fibrosis
Diagnosis
Exercise Test
Female
Gases
Hospitals, University
Humans
Lung - physiopathology
Lung diseases
Lung diseases, Obstructive
Lungs
Male
Methods
Middle Aged
Original Research
Oxygen saturation
Patients
Phenotype
Predictive Value of Tests
Pulmonary Disease, Chronic Obstructive - diagnosis
Pulmonary Disease, Chronic Obstructive - physiopathology
Pulmonary Ventilation
Severity of Illness Index
Spirometry
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Obstructive lung diseases of different etiologies present with progressive peripheral airway involvement. The peripheral airways, known as the silent lung zone, are not adequately evaluated with conventional function tests. The principle of gas washout has been used to detect pulmonary ventilation inhomogeneity and to estimate the location of the underlying disease process. Volumetric capnography (VC) analyzes the pattern of CO2 elimination as a function of expired volume. To measure normalized phase 3 slopes with VC in patients with non-cystic fibrosis bronchiectasis (NCB) and in bronchitic patients with chronic obstructive pulmonary disease (COPD) in order to compare the slopes obtained for the groups. NCB and severe COPD were enrolled sequentially from an outpatient clinic (Hospital of the State University of Campinas). A control group was established for the NCB group, paired by sex and age. All subjects performed spirometry, VC, and the 6-Minute Walk Test (6MWT). Two comparisons were made: NCB group versus its control group, and NCB group versus COPD group. The project was approved by the ethical committee of the institution. Statistical tests used were Wilcoxon or Student's t-test; P
ISSN:1178-2005
1176-9106
1178-2005
DOI:10.2147/COPD.S62886