Therapeutic Potential of Select Dietary Compounds in the Management of Hypertension and its Cardiovascular Complications

Hypertension is a common risk factor for cardiovascular disease and mortality worldwide. Proper nutrition and diet are known to play an indispensable role in the treatment and management of hypertension. Bioactive compounds that occur in small quantities in foods such as onions, fish and red wine ar...

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Bibliographic Details
Published in:Molecules (Basel, Switzerland) Switzerland), 2022-10, Vol.27 (21), p.7222
Main Authors: Valookaran, Aleena Francis, Bouchard, Jenny, Aloud, Basma Milad, Thandapilly, Sijo Joseph, Netticadan, Thomas
Format: Article
Language:English
Subjects:
Acids
Antihypertensives
Bioactive compounds
Biological activity
Blood pressure
Cardiovascular disease
Cardiovascular diseases
Chemical properties
Chronic diseases
Chronic illnesses
Clinical trials
Coenzyme Q10
Complications
Complications and side effects
Development and progression
Diet therapy
docosahexaenoic acid
eicosapentaenoic acid
Enzymes
Food
Health aspects
Health risks
Heart failure
Hypertension
Inflammation
Kidney diseases
Mortality
Nervous system
Nutrition
Omega-3 fatty acids
Pathogenesis
Pulmonary hypertension
Quality of life
Quercetin
Resveratrol
Review
Risk analysis
Risk factors
Tumor necrosis factor-TNF
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Summary:Hypertension is a common risk factor for cardiovascular disease and mortality worldwide. Proper nutrition and diet are known to play an indispensable role in the treatment and management of hypertension. Bioactive compounds that occur in small quantities in foods such as onions, fish and red wine are being intensively studied to uncover their vasoprotective, antioxidant, anti-proliferative and anti-inflammatory effects which are beneficial to attenuate chronic disease and protect human health. In this article, the anti-hypertensive, and cardio-protective effects of five food-derived bioactive compounds: resveratrol, quercetin, coenzyme Q10, DHA and EPA and their proposed mechanisms of action are reviewed in detail.
ISSN:1420-3049
1420-3049
DOI:10.3390/molecules27217222