Diet and Host Genetics Drive the Bacterial and Fungal Intestinal Metatranscriptome of Gilthead Sea Bream

The gut microbiota is now recognised as a key target for improving aquaculture profit and sustainability, but we still lack insights into the activity of microbes in fish mucosal surfaces. In the present study, a metatranscriptomic approach was used to reveal the expression of gut microbial genes in...

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Bibliographic Details
Published in:Frontiers in microbiology 2022-05, Vol.13, p.883738-883738
Main Authors: Naya-Català, Fernando, Piazzon, M Carla, Calduch-Giner, Josep A, Sitjà-Bobadilla, Ariadna, Pérez-Sánchez, Jaume
Format: Article
Language:English
Subjects:
archaea
bacteria
fungi
metatranscriptome
Microbiology
teleost fish
virus
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Summary:The gut microbiota is now recognised as a key target for improving aquaculture profit and sustainability, but we still lack insights into the activity of microbes in fish mucosal surfaces. In the present study, a metatranscriptomic approach was used to reveal the expression of gut microbial genes in the farmed gilthead sea bream. Archaeal and viral transcripts were a minority but, interestingly and contrary to rRNA amplicon-based studies, fungal transcripts were as abundant as bacterial ones, and increased in fish fed a plant-enriched diet. This dietary intervention also drove a differential metatranscriptome in fish selected for fast and slow growth. Such differential response reinforced the results of previously inferred metabolic pathways, enlarging, at the same time, the catalogue of microbial functions in the intestine. Accordingly, vitamin and amino acid metabolism, and rhythmic and symbiotic processes were mostly shaped by bacteria, whereas fungi were more specifically configuring the host immune, digestive, or endocrine processes.
ISSN:1664-302X
1664-302X
DOI:10.3389/fmicb.2022.883738