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The central nervous system microenvironment influences the leukemia transcriptome and enhances leukemia chemo-resistance

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Bibliographic Details
Published in:	Haematologica (Roma) 2017-04, Vol.102 (4), p.e136-e139
Main Authors:	Gaynes, Jeffrey S, Jonart, Leslie M, Zamora, Edward A, Naumann, Jordan A, Gossai, Nathan P, Gordon, Peter M
Format:	Article
Language:	English
Subjects:	Animals Antineoplastic Agents - pharmacology Bone Marrow Cells - drug effects Bone Marrow Cells - metabolism Bone Marrow Cells - pathology Central Nervous System - drug effects Central Nervous System - metabolism Central Nervous System - pathology Coculture Techniques Cytarabine - pharmacology Drug Resistance, Neoplasm - genetics Gene Expression Regulation, Leukemic Humans Mice Mice, Inbred NOD Neoplasm Proteins - genetics Neoplasm Proteins - metabolism Neoplasm Transplantation Neurons - metabolism Neurons - pathology Online Only Pre-B-Cell Leukemia Transcription Factor 1 - genetics Pre-B-Cell Leukemia Transcription Factor 1 - metabolism Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology Recurrence Signal Transduction Transcriptome Transplantation, Heterologous Tumor Microenvironment - genetics
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