Case report: late perianal mucinous adenocarcinoma after Crohn's disease proctectomy: an oncological rarity

As in ulcerative colitis, there is an increased incidence of colorectal carcinoma in Crohn's disease. While carcinoma formation originating from ano-rectal fistulas is generally considered as a rare event there are different publications reporting on mucinous adenocarcinoma formation in associa...

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Bibliographic Details
Published in:World journal of surgical oncology 2005-06, Vol.3 (1), p.42-42, Article 42
Main Authors: Keese, Michael, Back, Walter, Dinter, Dietmar, Gladisch, Rainer, Joos, Andreas, Palma, Pablo
Format: Article
Language:English
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Case Report
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Summary:As in ulcerative colitis, there is an increased incidence of colorectal carcinoma in Crohn's disease. While carcinoma formation originating from ano-rectal fistulas is generally considered as a rare event there are different publications reporting on mucinous adenocarcinoma formation in association with a neovagina and rectovaginal fistulas. To the best of our knowledge this is the first description of a perianal mucinous adenocarcinoma arising in a patient after Crohn's disease proctocolectomy. We report the case of a 50-year old female with a mucinous adenocarcinoma forming in the perineum eleven years after proctocolectomy for Crohn's disease. The patient was readmitted with perineal pain, leucocytosis and a perineal mass highly suspicious of abscess formation in the MRI-Scan. Histological examination revealed a mucinous adenocarcinoma. Exenteration including vagina, uterus and ovaries together with the coccygeal-bone was performed. Mucinous adenocarcinoma formation is a rare complication of Crohn's disease and so far unreported after proctocolectomy.
ISSN:1477-7819
1477-7819
DOI:10.1186/1477-7819-3-42