Echocardiographic myocardial strain analysis describes subclinical cardiac dysfunction after craniospinal irradiation in pediatric and young adult patients with central nervous system tumors

Craniospinal irradiation (CSI) is part of the treatment of central nervous system (CNS) tumors and is associated with cardiovascular disease in adults. Global myocardial strain analysis including longitudinal peak systolic strain (GLS), circumferential peak systolic strain (GCS), and radial peak sys...

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Bibliographic Details
Published in:Cardio-oncology (London, England) England), 2021-02, Vol.7 (1), p.5-7, Article 5
Main Authors: Martinez, Hugo R, Salloum, Ralph, Wright, Erin, Bueche, Lauren, Khoury, Philip R, Tretter, Justin T, Ryan, Thomas D
Format: Article
Language:English
Subjects:
Blood pressure
Brain cancer
Cancer therapies
Cardiac
Cardiomyopathy
Cardiovascular disease
Craniospinal irradiation
Hemoglobin
Laboratories
Nervous system
Neuro-oncology
Patients
Pediatrics
Software
Surveillance
Ultrasonic imaging
Young adults
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Summary:Craniospinal irradiation (CSI) is part of the treatment of central nervous system (CNS) tumors and is associated with cardiovascular disease in adults. Global myocardial strain analysis including longitudinal peak systolic strain (GLS), circumferential peak systolic strain (GCS), and radial peak systolic strain (GRS) can reveal subclinical cardiac dysfunction. Retrospective, single-center study in patients managed with CSI vs. age-matched controls. Clinical data and echocardiography, including myocardial strain analysis, were collected at early (
ISSN:2057-3804
2057-3804
DOI:10.1186/s40959-021-00093-z