Multi-triazole-resistant Aspergillus fumigatus and SARS-CoV-2 co-infection: A lethal combination

We report a case of severe COVID-19 pneumonia complicated by fatal co-infection with a multi-triazole resistant Aspergillus fumigatus and highlight the importance of recognising the significance of Aspergillus sp. isolation from respiratory samples. Early diagnosis and detection of triazole resistan...

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Bibliographic Details
Published in:Medical mycology case reports 2021-03, Vol.31, p.11-14
Main Authors: Mohamed, Aia, Hassan, Tidi, Trzos-Grzybowska, Marta, Thomas, Jubil, Quinn, Aidan, O'Sullivan, Maire, Griffin, Auveen, Rogers, Thomas R., Talento, Alida Fe
Format: Article
Language:English
Subjects:
CAPA Case Report
COVID-19 pneumonia
Invasive pulmonary aspergillosis
Multi-triazole resistance
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Summary:We report a case of severe COVID-19 pneumonia complicated by fatal co-infection with a multi-triazole resistant Aspergillus fumigatus and highlight the importance of recognising the significance of Aspergillus sp. isolation from respiratory samples. Early diagnosis and detection of triazole resistance are essential for appropriate antifungal therapy to improve outcome in patients with coronavirus associated invasive aspergillosis.
ISSN:2211-7539
2211-7539
DOI:10.1016/j.mmcr.2020.06.005