The role of B-type natriuretic peptide in the diagnosis of congestive heart failure in patients presenting to an emergency department with dyspnea

To determine the utility of B-type natriuretic peptide (BNP) in the diagnosis of congestive heart failure (CHF) in patients presenting with dyspnea to an emergency department (ED). Seventy patients presenting with dyspnea to an ED from April to July 2001 were included in the study. Mean age was 72+/...

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Bibliographic Details
Published in:Arquivos brasileiros de cardiologia 2002-12, Vol.79 (6), p.569-572
Main Authors: Villacorta, Humberto, Duarte, Adriana, Duarte, Neison Marques, Carrano, Angela, Mesquita, Evandro Tinoco, Dohmann, Hans J F, Ferreira, Francisco Eduardo G
Format: Article
Language:English
Subjects:
Aged
Atrial Natriuretic Factor - blood
Biomarkers - blood
CARDIAC & CARDIOVASCULAR SYSTEMS
Dyspnea - blood
Emergencies
emergency medicine
Female
heart failure
Heart Failure - blood
Heart Failure - diagnosis
Humans
Male
natriuretic peptides
Predictive Value of Tests
Sensitivity and Specificity
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Summary:To determine the utility of B-type natriuretic peptide (BNP) in the diagnosis of congestive heart failure (CHF) in patients presenting with dyspnea to an emergency department (ED). Seventy patients presenting with dyspnea to an ED from April to July 2001 were included in the study. Mean age was 72+/-16 years and 33 (47%) were male. BNP was measured in all patients at the moment of admission to the ED. Emergency-care physicians, blinded to BNP values, were required to assign a probable initial diagnosis. A cardiologist retrospectively reviewed the data (blinded to BNP measurements) and assigned a definite diagnosis, which was considered the gold standard for assessing the diagnostic performance of BNP. The mean BNP concentration was higher in patients with CHF (n=36) than in those with other diagnoses (990+/-550 vs 80+/-67 pg/mL, p
ISSN:0066-782X
1678-4170
1678-4170
DOI:10.1590/s0066-782x2002001500002