The Use of Fundus Autofluorescence in Dry Age-Related Macular Degeneration

Fundus autofluorescence (FAF) has been a well-known imaging method for quite some time. However, with developing technologies and novel imaging devices, FAF is being used more often to diagnose and monitor retinal diseases. The density of lipofuscin (LF) and other fluorophores in the retina have a d...

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Bibliographic Details
Published in:Turk oftalmoloji gazetesi 2021-06, Vol.51 (3), p.169-176
Main Authors: Kegkek, Nedime Sahinoglu, Cermet, Figen
Format: Article
Language:English
Subjects:
age-related macular degeneration
Fluorescein Angiography - statistics & numerical data
Fluorescence
fundus autofluorescence
Fundus Oculi
geographic atrophy
Geographic Atrophy - diagnosis
Humans
lipofuscin
Macula Lutea - diagnostic imaging
Macular degeneration
Prognosis
retina
Retinal Pigment Epithelium - diagnostic imaging
Review
Tıp
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Summary:Fundus autofluorescence (FAF) has been a well-known imaging method for quite some time. However, with developing technologies and novel imaging devices, FAF is being used more often to diagnose and monitor retinal diseases. The density of lipofuscin (LF) and other fluorophores in the retina have a determining role in FAF images. In dry age-related macular degeneration (AMD), hyperautofluorescence is seen in cases of increasing LF in the retina pigment epithelium, whereas hypoautofluorescence is detected in decreasing LF resulting from geographic atrophy. In recent years, studies have shown that FAF images provide prognostic information in patients with AMD. This review aims to highlight the importance of FAF imaging in dry AMD.
ISSN:1300-0659
2149-8709
2149-8695
2149-8709
2147-2661
DOI:10.4274/tjo.galenos.2020.49107